Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6145 |
ZM39923 hydrochloride
JAK3 Inhibitor IV,ZM 39923 HCl |
EGFR; Others; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells; Tyrosine Kinase/Adaptors |
ZM39923 hydrochloride (JAK3 Inhibitor IV) 是一种 JAK3抑制剂,pIC50值为 7.1。它也抑制组织型转谷氨酞胺酶 (TGM2) 的活性,IC50值为 10 nM。 | |||
T17295 | ZM39923 | Others | Others |
ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM). | |||
T2460 |
JAK 3 inhibitor IV
ZM 39923 hydrochloride,Jak3 inhibitor IV |
EGFR; Others; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells; Tyrosine Kinase/Adaptors |
JAK 3 inhibitor IV (ZM 39923 hydrochloride) 是一种 JAK1/3 抑制剂,pIC50 为 4.4/7.1,对 JAK2 几乎没有活性,对 EGFR 有适度的作用;还发现对转谷氨酰胺酶敏感。 |