Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2814 |
Cryptotanshinone
隐丹参酮,Cryptotanshinon,Tanshinone c,隐丹参醌 |
STAT; Autophagy | Autophagy; JAK/STAT signaling; Stem Cells |
Cryptotanshinone (Cryptotanshinon) 是从丹参的根中提取的一种天然产物,抑制STAT3的IC50为4.6 μM,具有抗肿瘤活性。 | |||
TN1980 |
Neocryptotanshinone
|
Others | Others |
Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid. | |||
TN1775 |
Isocryptotanshinone
|
ERK; JNK; STAT | JAK/STAT signaling; MAPK; Stem Cells |
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes. |