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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4271 |
Diroximel fumarate
Diroximel Fumarete |
Others | Others |
Diroximel fumarate (Diroximel Fumarete) 是一种控释制剂,是口服具有活力的富马酸单乙酯的前体药物。它被认为与其活性代谢物富马酸二甲酯的活性等效。它具有良好的安全性和有效性,具有研究多发性硬化的潜力。 | |||
T11045 |
Dimethyl fumarate-d6
Dimethyl fumarate D6,DMF D6 |
Others | Others |
Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0492 |
Dimethyl fumarate
富马酸二甲酯,DMF |
Reactive Oxygen Species; HIV Protease; Nrf2; Endogenous Metabolite; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Dimethyl fumarate (DMF) 是具有口服活性且可透过血脑屏障的Nrf2激活剂,可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物,可作抗炎和免疫调节剂,可研究多发性硬化症。 |