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Cat. No. Product Name Target Signaling Pathways
T6918 Olmutinib

HM61713, BI 1482694,奥莫替尼,BI 1482694,HM61713

EGFR; BTK Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Olmutinib (HM61713, BI 1482694) 是可口服的不可逆 EGFR 酪氨酸激酶抑制剂,其与激酶结构域附近的半胱氨酸残基结合,可用于非小细胞肺癌的研究。
T8460 Olmutinib

HM61713,BI1482694

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Olmutinib (BI1482694) 是一种新型表皮生长因子受体酪氨酸激酶抑制剂。
T70128 Olmutinib hydrochloride

Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor, used in the treatment of T790M mutation positive non-small cell lung cancer. Olmutinib covalently binds a cysteine residue near the kinase domain of mutant EGFRs to prevent phosphorylation of the receptor. EGFRs are frequently over-expressed in lung cancer and contribute to activation of the phosphoinositide 3-kinase and mitogen-activated protein kinase pathways which both p...

化合物

Olmutinib
Cat.No: T6918
Synonym: HM61713, BI 1482694,奥莫替尼,BI 1482694,HM61713
Target: EGFR, BTK
Olmutinib
Cat.No: T8460
Synonym: HM61713,BI1482694
Target: EGFR
Olmutinib hydrochloride
Cat.No: T70128
Synonym:
Target:
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