Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1593 |
Ezetimibe
依泽替米贝,SCH 58235 |
Others; Nrf2; NPC1L1; Autophagy | Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others |
Ezetimibe (SCH 58235) 是一种膳食胆固醇吸收抑制剂。它是一种NPC1L1抑制剂,是有效的Nrf2激活剂。 | |||
T11253 |
Ezetimibe phenoxy glucuronide
依泽替米贝葡糖苷酸,Ezetimibe β-D-glucuronide,Ezetimibe glucuronide |
Others | Others |
Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity. | |||
T11003 |
Desfluoro-ezetimibe
|
Others | Others |
Desfluoro-ezetimibe is the defluorinated impurity of ezetimibe. Ezetimibe is an effective, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor and an effective Nrf2 activator. |