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Cat. No.	Product Name	Target	Signaling Pathways
TP1303	β-Amyloid (1-40) β-Amyloid 1-40
	Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.
T39285	Biotin-β-Amyloid (1-40)
	Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid- -(1-40) peptide.
TP1441	β-Amyloid (1-40) (rat) Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠)
	Rat form of the beta-Amyloid (1-40) peptide
T39146	β-Amyloid (1-40), FAM-labeled
	β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ ex = 492 nm and λ em = 518 nm).
T75751	β-Amyloid (1-40) (TFA)
	β-Amyloid (1-40) TFA 是阿尔茨海默症患者脑斑块中发现的一种主要蛋白片段。
T76086	β-Amyloid (1-40), FAM-labeled TFA
	β-Amyloid (1-40), FAM-labeled TFA 是一个 FAM 荧光标记的 β-Amyloid (1-40) 肽 (λex=?492?nm and λem=?518?nm)。
T83507	[Asn23] β-Amyloid (1-40), Iowa mutation
	[Asn23] β-Amyloid (1-40), Iowa mutation 是一种与重度大脑淀粉样蛋白血管病 (CAA) 相关的生物活性肽。该突变涉及 APP 694 位点的错义突变，Asp 23 位置的天冬酰胺被天冬酰氨酸取代。这种变异的 β-Amyloid 肽倾向于更快聚集，并形成有害的原纤维。
T83283	5-TAMRA-Amyloid β-Protein (1-40)
	5-TAMRA-Amyloid β-Protein (1-40)为荧光 (TAMRA) 标记的淀粉样β-蛋白（Amyloid β-Protein）(1-40)片段, 其吸收和发射峰值分别位于Abs/Em=544/572 nm。
T83509	[Arg6]-β-Amyloid (1-40), england mutation
	[Arg6]-β-Amyloid (1-40), England mutation 是具有生物活性的肽，与多种家族性常染色体显性阿尔茨海默病相关。特别地，这种英国突变，即位于第6位的His被Arg所替换，已报告可提高寡聚体形成动力学，加速初级纤维的种子化过程。此类寡聚体对神经元培养细胞展现出较高毒性。
T83541	(Gln22,Asn23)-Amyloid β-Protein (1-40)
	(Gln22,Asn23)-Amyloid β-Protein (1-40) 为特定多肽，主要应用于研究脑淀粉样血管病的相关突变。
T83540	(Gly22)-amyloid beta-protein(1-40)
	(Gly22)-amyloid beta-protein(1-40) (Arctic variant Ab40ARC (E22G)) 是用于阿尔茨海默病研究的肽。
T3521	γ-Secretase-IN-1 Compound E	Beta Amyloid; Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	γ-Secretase-IN-1 是一种高效的 γ-secretase 抑制剂，对T-47D 细胞显示部分抗增殖活性且抑制 β-amyloid(40)，β-amyloid(42)，和Notch γ-分泌酶裂解。
T4364	Aftin-4 Aftin 4,Aftin4	Beta Amyloid; Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Aftin-4 是一种 β-淀粉样蛋白42(Aβ42) 的诱导剂。
T83539	(Pyr11)-Amyloid β-Protein (11-40)
	(Pyr11)-Amyloid β-Protein (11-40) (A beta 11pE-40) 作为一种肽，主要应用于阿尔茨海默病相关研究。
T76087	Biotin-β-Amyloid (17-40)
	Biotin-β-Amyloid (17-40) 是 N 端标记的生物素化的β-Amyloid (17-40) 肽段。该化合物为 Aβ 蛋白中的 24 个氨基酸残基构成的片段，源自于淀粉样前体蛋白(APP)的翻译及加工过程。
T19142	4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine	Beta Amyloid	Neuroscience
	4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).
T76434	Biotinyl-Amyloid β-Protein (1-42) (ammonium)
	Biotinyl-Amyloid β-Protein (1-42) ammonium 是一种生物素化的 Amyloid β-Protein (1-42). Amyloid β-Protein (1-42) ammonium 可用于 Aβ1-42 在大脑中转化为 Aβ1-40 的研究。
T83204	Acetly-β Amyloid(15-20), Amide
	Acetly-β Amyloid (15-20), Amide 为多肽片段，具有抑制 Aβ (1–40) 肽β-折叠形成并稳定其结构的功能，适用于阿尔茨海默病的相关研究。
T37531	Glycerophosphorylethanolamine (sodium salt)
	Glycerophosphorylethanolamine is an active phosphodiester metabolite of phosphatidylethanolamine.1,2It promotes aggregation of amyloid-β (1-40) (Aβ40)in vitro, and levels of glycerophosphorylethanolamine are elevated in postmortem brains isolated from patients with Alzheimer’s disease. 1.Klunk, W.E., Xu, C.J., McClure, R.J., et al.Aggregation of β-amyloid peptide is promoted by membrane phospholipid metabolites elevated in Alzheimer’s disease brainJ. Neurochem.69(1)266-272(1997) 2.Blusztajn, J.K...
T35627	Amylin (human) (trifluoroacetate salt)
	Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values of 2 and 0.2 nM for porcine and guinea pig nucleus accumbens membrane preparations, respectively. Amylin is present in amyloid aggregates derived from the pancreatic islets of humans with type 2 diabetes. Amylin forms fibrils that react to thioflavin T and are organized in a cro...
T37370	Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
	Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM....
T37369	Amyloid-β (1-8, A2V) Peptide Amyloid-β (1-8, A2V) Peptide
	Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Aβ (1-40) (Aβ40) A2V peptide increases the production of Aβ and the rate and amount of amyloid fibril formation in vitro, effects that can be reduced by coincubation with wild-type Aβ40. Aβ40 and Aβ42 levels are increased in CHO ...
T36911	Pramlintide (acetate hydrate)
	Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human amylin receptor 1a (AMY1a), AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively). Pramlintide inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner. In vivo, pramlintide (200 pg/kg) reduces brain levels of amyloid-β (1-40) and incr...

化合物

β-Amyloid (1-40)

Cat.No: TP1303

Synonym: β-Amyloid 1-40

Biotin-β-Amyloid (1-40)

Cat.No: T39285

β-Amyloid (1-40) (rat)

Cat.No: TP1441

Synonym: Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠)

β-Amyloid (1-40), FAM-labeled

Cat.No: T39146

β-Amyloid (1-40) (TFA)

Cat.No: T75751

β-Amyloid (1-40), FAM-labeled TFA

Cat.No: T76086

[Asn23] β-Amyloid (1-40), Iowa mutation

Cat.No: T83507

5-TAMRA-Amyloid β-Protein (1-40)

Cat.No: T83283

[Arg6]-β-Amyloid (1-40), england mutation

Cat.No: T83509

(Gln22,Asn23)-Amyloid β-Protein (1-40)

Cat.No: T83541

(Gly22)-amyloid beta-protein(1-40)

Cat.No: T83540

γ-Secretase-IN-1

Cat.No: T3521

Synonym: Compound E

Target: Beta Amyloid, Gamma-secretase

Cat.No: T4364

Synonym: Aftin 4,Aftin4

Target: Beta Amyloid, Gamma-secretase

(Pyr11)-Amyloid β-Protein (11-40)

Cat.No: T83539

Biotin-β-Amyloid (17-40)

Cat.No: T76087

4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine

Cat.No: T19142

Target: Beta Amyloid

Biotinyl-Amyloid β-Protein (1-42) (ammonium)

Cat.No: T76434

Acetly-β Amyloid(15-20), Amide

Cat.No: T83204

Glycerophosphorylethanolamine (sodium salt)

Cat.No: T37531

Amylin (human) (trifluoroacetate salt)

Cat.No: T35627

Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

Cat.No: T37370

Amyloid-β (1-8, A2V) Peptide

Cat.No: T37369

Synonym: Amyloid-β (1-8, A2V) Peptide

Pramlintide (acetate hydrate)

Cat.No: T36911

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