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Search Results for " (±) carnitine chloride "

20

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37735	Stearoyl-L-carnitine chloride C18 Carnitine,Stearoylcarnitine chloride
	Stearoyl-L-carnitine chloride（Acylcarnitine C18:0）是一种存在于小脑中的长链酰基肉碱，抑制 GlyT2 ，是研究脂代谢的重要组成部分。
T37359	Myristoyl-L-carnitine chloride L-Myristoylcarnitine chloride	Endogenous Metabolite	Metabolism
	Myristoyl-L-carnitine chloride (L-Myristoylcarnitine chloride) 是人体的代谢物之一，与遗传代谢疾病有关。Tetradecanoylcarnitine 是研究糖尿病和自身免疫性肝炎的潜在标记物。
T38253	Lauroyl-L-carnitine (chloride) Lauroyl-L-carnitine Hydrochloride
	Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride)是一种酰基肉碱和表面活性剂，已被用于渗透猪肠细胞，以输送极性荧光探针荧光黄。
T37407	Arachidonoyl-L-carnitine (chloride) C20:4 Carnitine,Arachidonoyl-L-carnitine (chloride)
	Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. β-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alte...
T38232	Heptanoyl-L-carnitine (chloride)
	Heptanoyl-L-carnitine is a medium-chain acylcarnitine and derivative of L-carnitine .
T36050	Linoleoyl-L-carnitine (chloride)
	Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg/kg) administration of isoniazid in mice.
T37453	Butyryl-L-carnitine (chloride)
	Butyryl-L-carnitine is a butyrate ester of carnitine. It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human retinal pigment epithelial (HRPE) cells (IC50s = 1.5 μM and 4.6 mM, respectively).
T36098	Isovaleryl-L-carnitine (chloride)
	Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated wit...
T13810	Palmitoylcarnitine chloride Palmitoyl DL-carnitine chloride	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) 是一种线粒体脂肪酸氧化中间体，可介导脂质内心脏保护。Palmitoylcarnitine chloride 通过消耗谷胱甘肽来消除结直肠癌细胞的存活，诱导癌细胞死亡，调节蛋白激酶 C βII 与其受体 RACK1 之间的相互作用。
T38267	Valeryl-L-carnitine (chloride) Valeryl-L-carnitine (chloride),L-Valerylcarnitine
	Valeryl-L-carnitine is a short-chain acylcarnitine and a derivative of L-carnitine . Valeryl-L-carnitine levels increase in the serum of rhesus monkeys following exposure to 7 and 10 Gray units (Gy) of ionizing radiation.[1]
T37245	Palmitoyl-D-carnitine (chloride)
	Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palmitoylcarnitine synthesis by erythrocyte membranes.
T36663	Decanoyl-L-carnitine (chloride)
	Decanoyl-L-carnitine is an ester derivative of L-carnitine . It increases the formation of C24 fatty acid intermediates, as well as docosapentaenoic and docosahexaenoic acid in rat hepatocytes.
T38233	Hexanoyl-L-carnitine (chloride)
	Hexanoyl-L-carnitine is a medium-chain acylcarnitine. It has been used in the synthesis of acylcarnitine benzyl esters.1 1.Gong, X.-w., Li, J.-p., Wu, J.-f., et al.Synthesis of carnitine benzyl esters as prodrugsJ. Chem. Res.2008(6)327-330(2008)
T22484	(±)-Propionylcarnitine chloride Propionyl-DL-carnitine chloride	Endogenous Metabolite	Metabolism
	(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) 是一种短链酰基肉碱的混合物，可用作膳食补充剂，可用于研究慢性糖尿病。
T37299	L-Palmitoylcarnitine chloride
	Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant...
T1182	Levocarnitine propionate hydrochloride Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Levocarnitine propionate hydrochloride (ST-261) 可用于肾功能恶化，充血性心脏衰竭，间歇性跛行等疾病的研究。
T73766	Isobutyryl-L-carnitine chloride
	Isobutyryl-L-carnitine chloride 是酰基辅酶 A 脱氢酶的产物。
TMIH-0296	L-Carnitine-d3 Chloride
	L-Carnitine-d3 Chloride 是 L-Carnitine Chloride 的氘代化合物。
T83872	Oleoyl-L-carnitine chloride L-Carnitine oleoyl ester,L-Octadecanoylcarnitine,C18:1 Carnitine,CAR 18:1
	Oleoyl-L-carnitine是一种长链酰基肉碱，也是一种糖苷转运体2（GlyT2；IC50 = 340 nM）的抑制剂，对GlyT2比对GlyT1（IC50 = >10,000 nM）具有选择性。慢性肾脏病或接受初始血液透析的终末期肾脏病患者的血浆中Oleoyl-L-carnitine水平增高，这与心血管死亡率相关。
TMIH-0071	Acetyl L-Carnitine-d3 Chloride
	Acetyl L-Carnitine-d3 Chloride 是 Acetyl L-Carnitine Chloride 的氘代化合物。

化合物

Stearoyl-L-carnitine chloride

Cat.No: T37735

Synonym: C18 Carnitine,Stearoylcarnitine chloride

Myristoyl-L-carnitine chloride

Cat.No: T37359

Synonym: L-Myristoylcarnitine chloride

Target: Endogenous Metabolite

Lauroyl-L-carnitine (chloride)

Cat.No: T38253

Synonym: Lauroyl-L-carnitine Hydrochloride

Arachidonoyl-L-carnitine (chloride)

Cat.No: T37407

Synonym: C20:4 Carnitine,Arachidonoyl-L-carnitine (chloride)

Heptanoyl-L-carnitine (chloride)

Cat.No: T38232

Linoleoyl-L-carnitine (chloride)

Cat.No: T36050

Butyryl-L-carnitine (chloride)

Cat.No: T37453

Isovaleryl-L-carnitine (chloride)

Cat.No: T36098

Palmitoylcarnitine chloride

Cat.No: T13810

Synonym: Palmitoyl DL-carnitine chloride

Target: PKC

Valeryl-L-carnitine (chloride)

Cat.No: T38267

Synonym: Valeryl-L-carnitine (chloride),L-Valerylcarnitine

Palmitoyl-D-carnitine (chloride)

Cat.No: T37245

Decanoyl-L-carnitine (chloride)

Cat.No: T36663

Hexanoyl-L-carnitine (chloride)

Cat.No: T38233

(±)-Propionylcarnitine chloride

Cat.No: T22484

Synonym: Propionyl-DL-carnitine chloride

Target: Endogenous Metabolite

L-Palmitoylcarnitine chloride

Cat.No: T37299

Levocarnitine propionate hydrochloride

Cat.No: T1182

Synonym: Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐

Target: Histamine Receptor

Isobutyryl-L-carnitine chloride

Cat.No: T73766

L-Carnitine-d3 Chloride

Cat.No: TMIH-0296

Oleoyl-L-carnitine chloride

Cat.No: T83872

Synonym: L-Carnitine oleoyl ester,L-Octadecanoylcarnitine,C18:1 Carnitine,CAR 18:1

Acetyl L-Carnitine-d3 Chloride

Cat.No: TMIH-0071

Cat. No.	Product Name	Target	Signaling Pathways
T6475	(±)-Carnitine chloride Monocamin,DL-Carnitine HCl,Bicarnesine,混旋肉碱盐酸盐,DL-Carnitine chloride	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	(±)-Carnitine chloride (Monocamin) 有D 和L 两种异构体。其中 L-carnitine 在脂肪酸的 β-氧化中起重要作用，也具有抗氧化作用和抗炎活性。
T20123	L-Carnitine hydrochloride L-Carnitine chloride,LC 80,Levocarnitine chloride,(R)-Carnitine hydrochloride,LC-80,LC80
	Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. Carnitine is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It has also been used to allow the en
T4702	(3-Carboxypropyl)trimethylammonium chloride γ-Butyrobetaine hydrochloride,(3-羧丙基)三甲基氯化铵,(3-Carboxypropyl)trimethylammonium chlor	Endogenous Metabolite	Metabolism
	(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) 一种血管病变性中间代谢物，是由肠道微生物代谢产生，这些微生物以红肉中的肉碱为食。
T5066	Nε,Nε,Nε-Trimethyllysine chloride Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) 是肠道菌群依赖性形成 N,N,N-trimethyl-5-aminovaleric acid (TMAVA) 的前体。

天然产物

(±)-Carnitine chloride

Cat.No: T6475

Synonym: Monocamin,DL-Carnitine HCl,Bicarnesine,混旋肉碱盐酸盐,DL-Carnitine chloride

Target: Reactive Oxygen Species

L-Carnitine hydrochloride

Cat.No: T20123

Synonym: L-Carnitine chloride,LC 80,Levocarnitine chloride,(R)-Carnitine hydrochloride,LC-80,LC80

(3-Carboxypropyl)trimethylammonium chloride

Cat.No: T4702

Synonym: γ-Butyrobetaine hydrochloride,(3-羧丙基)三甲基氯化铵,(3-Carboxypropyl)trimethylammonium chlor

Target: Endogenous Metabolite

Nε,Nε,Nε-Trimethyllysine chloride

Cat.No: T5066

Synonym: Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride

Target: Others, Endogenous Metabolite

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