Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) 是肠道菌群依赖性形成 N,N,N-trimethyl-5-aminovaleric acid (TMAVA) 的前体。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 560 | 35日内发货 | ||
10 mg | ¥ 1,060 | 35日内发货 | ||
25 mg | ¥ 1,620 | 35日内发货 |
产品描述 | Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxidation. Nε,Nε,Nε--Trimethyl-L-lysine residues are found in a number of proteins and are generated by the action of S-adenosyl-L-methionine on exposed lysine residues. When trimethyllysine is released from cognate proteins via proteolysis, it serves as a precursor for carnitine biosynthesis. Mitochondrial 6-N-trimethyllysine dioxygenase converts 6-N-trimethyllysine to 3-hydroxy-6-N-trimethyllysine as the first step for carnitine biosynthesis. |
别名 | Lys(Me)3-OH Chloride, Nε,Nε,Nε-Trimethyllysine hydrochloride |
分子量 | 224.73 |
分子式 | C9H21ClN2O2 |
CAS No. | 55528-53-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.4498 mL | 22.2489 mL | 44.4978 mL | 111.2446 mL |
5 mM | 0.89 mL | 4.4498 mL | 8.8996 mL | 22.2489 mL | |
10 mM | 0.445 mL | 2.2249 mL | 4.4498 mL | 11.1245 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Nε,Nε,Nε-Trimethyllysine chloride 55528-53-5 Metabolism Others Endogenous Metabolite Nε,Nε,Nε-Trimethyllysine microbe Nε,Nε,NεTrimethyllysine chloride intestinal Nε,Nε,Nε-Trimethyllysine Hydrochloride metabolite Nε,Nε,Nε Trimethyllysine chloride TMAVA inhibit Lys(Me)3-OH Chloride Inhibitor Nε,Nε,Nε-Trimethyllysine Chloride Nε,Nε,Nε-Trimethyllysine hydrochloride inhibitor