IL-T4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAH36827.1.
生物活性 | Testing in progress |
产品描述 | IL-T4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAH36827.1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | AAH36827.1 |
别名 | ILT-4, ILT4, LIR-2, CD85D, MIR10, leukocyte immunoglobulin like receptor B2, LIR2, MIR-10 |
蛋白构建 | The Human LILRB2 (AAH36827.1) (Met1-Val461) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro. |
蛋白纯度 | > 90 % as determined by SDS-PAGE |
分子量 | 49.2 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
IL-T4 Protein, Human, Recombinant (His), Biotinylated ILT-4 ILT4 LIR-2 CD85D LIR 2 MIR10 leukocyte immunoglobulin like receptor B2 LIR2 MIR-10 ILT 4 MIR 10 recombinant recombinant-proteins proteins protein