血管内皮生长因子受体 (Vascular Endothelial Growth Factor Receptors, VEGFRs) 是血管内皮生长因子(Vascular Endothelial Growth Factor ,VEGF)的受体。VEGFR有三种主要亚型,编号为1、2和3。根据选择性剪接,它们可能是膜结合的 (mbVEGFR) 或可溶的 (sVEGFR)。 VEGFR的细胞外部分由 7 个免疫球蛋白样结构域、一个跨膜区域和一个包含分裂酪氨酸激酶结构域的细胞内部分组成。VEGFR-2 似乎介导了几乎所有已知的细胞对 VEGF 的反应。VEGFR-1 的功能尚不明确,尽管它被认为可以调节 VEGFR-2 信号传导。VEGFR-1 的另一个功能是充当虚拟/诱饵受体,将 VEGF 从 VEGFR-2 结合中隔离出来。VEGFR-1 (sFlt1) 的可变剪接形式不是膜结合蛋白,而是分泌的,主要用作诱饵。VEGFR-3 介导淋巴管生成以响应 VEGF-C 和 VEGF-D。VEGFR抑制剂用于治疗癌症。
Cat. No. | Product Name / Synonyms | Species | Expression System |
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TMPY-04795 | VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
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Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and th... | |||
TMPY-04796 | VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
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Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the ... | |||
TMPY-04802 | VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
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Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the ... | |||
TMPY-04924 | VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
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Mouse | HEK293 Cells |
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and th... | |||
TMPY-04940 | VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and th... | |||
TMPY-05382 | VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.7 kDa and the accessi... | |||
TMPY-05610 | VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 8... | |||
TMPY-05657 | VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
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Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and th... | |||
TMPY-05733 | FLT1 Protein, Mouse, Recombinant (His)
FLT1 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
FLT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number i... | |||
TMPY-06620 | VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is ... | |||
TMPY-06665 | FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
|
Mouse | HEK293 Cells |
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.34 k... | |||
TMPY-06780 | FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 85.45 k... | |||
TMPY-01936 | VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession n... | |||
TMPY-00637 | FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His)
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Human | HEK293 Cells |
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accessio... | |||
TMPY-00949 | VEGFR3/FLT4 Protein, Human, Recombinant (His)
VEGFR3/FLT4 Protein, Human, Recombinant (His)
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Human | HEK293 Cells |
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession num... | |||
TMPY-02361 | VEGFR2/KDR Protein, Human, Recombinant (His)
VEGFR2/KDR Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession nu... | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protei... |