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SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)

产品编号 TMPY-03296
别名: SH-PTP1, Hcph, 70Z-SHP, Ptp1C, protein tyrosine phosphatase, non-receptor type 6, me, hcp, PTPTY-42, SHP-1

PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of PTPN6 with its substrates. PTPN6 is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. It has been shown that PTPN6 interacts with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.

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SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) Chemical Structure
SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST), CAS N/A
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) 的其他形式现货产品:

MMP-12 Protein, Human, Recombinant (catalytic domain) SIRP alpha Protein, Mouse, Recombinant (His)
产品目录号及名称: SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) (TMPY-03296)
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参考文献
产品描述 PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of PTPN6 with its substrates. PTPN6 is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. It has been shown that PTPN6 interacts with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.
别名 SH-PTP1, Hcph, 70Z-SHP, Ptp1C, protein tyrosine phosphatase, non-receptor type 6, me, hcp, PTPTY-42, SHP-1
分子量 72.7 kDa (predicted)

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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TargetMol Library Books参考文献

1. Yu CL,et al.(2000) Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation. J Biol Chem. 275(1):599-604. 2. Wu DW,et al.(2000) SH2-Containing protein tyrosine phosphatase-1 (SHP-1) association with Jak2 in UT-7/Epo cells. Blood Cells Mol Dis. 26(1):15-24. 3. Jiao H,et al.(1996) Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1. Mol Cell Biol. 16(12):6985-92.

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Keywords

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) SH-PTP1 Hcph 70Z-SHP SHP 1 Ptp1C protein tyrosine phosphatase, non-receptor type 6 me hcp PTPTY 42 SHP1 PTPTY-42 SHP-1 PTPTY42 Inhibitor inhibitor inhibit

 

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