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MPO Protein, Mouse, Recombinant (His)

MPO Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00833   CAS TMPJ-00833
别名: MPO, Myeloperoxidase

Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride, bromide, and iodide to multiple reactive species. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. Modification of ApoB100, as well as the lipid and cholesterol components of LDL and HDL, promotes the development of atherosclerosis. MPO is also associated with a variety of other diseases, and inhibits vasodilation in inflammation by depleting the levels of NO. Serum albumin functions as a carrier protein during MPO movement to the basolateral side of epithelial cells. MPO is stored in neutrophil azurophilic granules. Upon cellular activation, it is deposited into pathogencontaining phagosomes. While mice lacking MPO are impaired in clearing select microbial infections,MPO deficiency in humans does not necessarily result in heightened susceptibility to infections.

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MPO Protein, Mouse, Recombinant (His) Chemical Structure
MPO Protein, Mouse, Recombinant (His), CAS TMPJ-00833
规格 价格/CNY 货期 数量
10 μg ¥ 820 5日内发货
50 μg ¥ 2,480 5日内发货
500 μg ¥ 11,000 5日内发货
1 mg ¥ 17,400 5日内发货

MPO Protein, Mouse, Recombinant (His) 的其他形式现货产品:

MPO
其他形式的 MPO Protein, Mouse, Recombinant (His):
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: MPO Protein, Mouse, Recombinant (His) (TMPJ-00833)
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产品描述 Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride, bromide, and iodide to multiple reactive species. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. Modification of ApoB100, as well as the lipid and cholesterol components of LDL and HDL, promotes the development of atherosclerosis. MPO is also associated with a variety of other diseases, and inhibits vasodilation in inflammation by depleting the levels of NO. Serum albumin functions as a carrier protein during MPO movement to the basolateral side of epithelial cells. MPO is stored in neutrophil azurophilic granules. Upon cellular activation, it is deposited into pathogencontaining phagosomes. While mice lacking MPO are impaired in clearing select microbial infections,MPO deficiency in humans does not necessarily result in heightened susceptibility to infections.
别名 MPO, Myeloperoxidase
分子量 90-100 KDa (reducing condition)
CAS No. TMPJ-00833

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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Keywords

MPO Protein, Mouse, Recombinant (His) TMPJ-00833 MPO Myeloperoxidase Inhibitor inhibitor inhibit

 

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