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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T35805 C16 Sphingomyelin (d18:1/16:0)

Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin

Endogenous Metabolite Metabolism
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) 是磷脂双层膜的磷脂类化合物,可用于研究生物膜的活性。
T36859 C16 Globotriaosylceramide (d18:1/16:0)

C16 Globotriaosylceramide (d18:1/16:0)

C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. C16 globotriaosylceramide is also upregulated in plasma of patien...
T37872 C16 Galactosylceramide (d18:1/16:0)

C16 Galactosylceramide (d18:1/16:0)

C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
T35804 C16 Lactosylceramide (d18:1/16:0)

C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle. C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.
T37562 C16 Ceramide

N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine

p53 Apoptosis
C16 Ceramide (Palmitoyl Ceramide) 是一种天然小分子,通过直接选择性结合激活 p53。
T36149 13C C16 Sphingomyelin (d18:1/16:0)

13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a form of sphingomyelin containing palmitate (16:0) at the variable acylation position. It is the most common form of sphingomyelin found in eggs and is less abundant in the brain and in milk. C16 Sphingomyelin interacts with cholesterol in or...
T37454 C16 dihydro Ceramide (d18:0/16:0)

Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine

C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability ...

化合物

C16 Sphingomyelin (d18:1/16:0)
Cat.No: T35805
Synonym: Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin
Target: Endogenous Metabolite
C16 Globotriaosylceramide (d18:1/16:0)
Cat.No: T36859
Synonym: C16 Globotriaosylceramide (d18:1/16:0)
Target:
C16 Galactosylceramide (d18:1/16:0)
Cat.No: T37872
Synonym: C16 Galactosylceramide (d18:1/16:0)
Target:
C16 Lactosylceramide (d18:1/16:0)
Cat.No: T35804
Synonym:
Target:
C16 Ceramide
Cat.No: T37562
Synonym: N-acylsphingosine,C16 Ceramide (d18:1/16:0),Palmitoyl Ceramide,N-Palmitoylsphingosine
Target: p53
13C C16 Sphingomyelin (d18:1/16:0)
Cat.No: T36149
Synonym:
Target:
C16 dihydro Ceramide (d18:0/16:0)
Cat.No: T37454
Synonym: Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine
Target:
Cat. No. Product Name Target Signaling Pathways
T38179 C16 3'-sulfo Galactosylceramide (d18:1/16:0)

C16 3'-sulfo Galactosylceramide (d18:1/16:0)

Others Others
C16 3'-sulfo Galactosylceramide (d18:1/16:0)是硫酸盐类糖脂的一种。C16 3'-sulfo Galactosylceramide (d18:1/16:0)是在猪脑和血浆中发现的一种比较丰富的硫化物,在小鼠的整个发育过程中会有所减少。C16 3'-sulfo Galactosylceramide (d18:1/16:0)在体外可抑制视网膜神经节细胞生长。C16 3'-sulfo Galactosylceramide (d18:1/16:0)已被用作量化大鼠小脑和多发性硬化症患者分离的白质中的硫化物的参照物。
T82572 D-Glucosyl-β-1,1′-N-palmitoylsphingosine

C16 Glucosyl(β) Ceramide (d18:1/16:0)

D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) 是内源性Mincle配体,具免疫刺激活性。

天然产物

C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Cat.No: T38179
Synonym: C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Target: Others
D-Glucosyl-β-1,1′-N-palmitoylsphingosine
Cat.No: T82572
Synonym: C16 Glucosyl(β) Ceramide (d18:1/16:0)
Target:
TargetMol Loading
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