COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.

Cat. No.	Product Name	CAS No.	Purity
T16291	NF157 化合物 T16291	104869-26-3	98%
T16291	NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly s...
T16464	Pelubiprofen 化合物 T16464	69956-77-0	98%
T16464	Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway. It also has significant anti-inflammatory ...
TN4038	Eupatolide 泽兰内酯	6750-25-0	98%
TN4038	Eupatolide 是从 Inula japonica 的花中分离出来的，具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
TN3587	Capillarisin 化合物 TN3587	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T12227	Nimesulide D5 化合物 T12227	1330180-22-7	98%
T12227	Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM)
TN3410	Anatabine 化合物 TN3410	581-49-7	98%
TN3410	Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheime...
TN4752	Perilloxin 化合物 TN4752	263249-77-0	98%
TN4752	Perilloxin possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 microM.
TN1171	6-Dehydrogingerdione 1-脱氢-6-姜酮	76060-35-0	98%
TN1171	1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
T4131	Arjunic acid 化合物 T4131	31298-06-3	98%
T4131	Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values r...
TN3708	Coronarin D 化合物 TN3708	119188-37-3	98%
TN3708	Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
TN1374	α-Chaconine 阿尔法卡茄碱	20562-03-2	98%
TN1374	Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Al...
T11296	Flosulide 化合物 T11296	80937-31-1	98%
T11296	Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.
TN5011	Shizukaol B 化合物 TN5011	142279-40-1	98%
TN5011	Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
TN1606	(-)-Epiafzelechin 表阿夫儿茶精	24808-04-6	98%
TN1606	(-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX acti...
T15345	FR-188582 化合物 T15345	189699-82-9	98%
T15345	FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).
TN1062	Peonidin chloride 氯化芍药素	134-01-0	98%
TN1062	Peonidin chloride has antioxidant activity. Peonidin has show potent inhibitory and apoptotic effects on cancer cells in vitro, notably metastatic human breast c...
TN1871	Ligustroside 女贞甙	35897-92-8	98%
TN1871	Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustrosid...
TN1510	Clematomandshurica saponin B 化合物Clematomandshurica saponin B	916649-91-7	98%
TN1510	Clematomandshurica saponin B shows significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.58 microM).
TN3805	Dehydrogeijerin 化合物 TN3805	16850-91-2	98%
TN3805	Dehydrogeijerin significantly inhibits the inflammatory activity of activated macrophages, suggesting that it could be a potential candidate for the treatment of...
TN3482	Bakkenolide B 化合物 TN3482	18455-98-6	98%
TN3482	Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.