Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20225 |
Dicentrine, (-)-
L-Dicentrine,荷包牡丹碱,NSC 251699,NSC251699,NSC-251699 |
Others | Others |
Dicentrine, (-)- (NSC-251699) 是一种在几种植物物种中发现的非卟啉生物碱,在小鼠内脏痛的急性模型中显示出显著的镇痛活性。 | |||
T2850 |
Bicuculline
荷包牡丹碱,(+)-Bicuculline,d-Bicuculline |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Bicuculline ((+)-Bicuculline) 是从东北延胡索中提取的一种生物碱,能阻断 Ca2+激活钾 (SK) 通道。它是一种竞争性的神经递质 GABAA 受体拮抗剂,IC50为 2 μM。 | |||
TN1577 |
Dicentrine
荷苞牡丹碱,荷包牡丹碱 |
Others | Others |
Dicentrine, a selective α±(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities, it also has antinociception in different models of chemical pain. | |||
TN1559 |
Dehydrodicentrine
|
AChR | Neuroscience |
Dehydrodicentrine showed strong acetylcholinesterase (AChE) inhibitory effects with the IC50 value of 2.98 μM. |