Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6134 |
IEM 1754 2HBr
IEM 1754 dihydrobromide |
GluR | Neuroscience |
IEM 1754 2HBr (IEM 1754 dihydrobromide) 是一种选择性 AMPA/红藻氨酸受体阻滞剂,作用于 GluR1 和 GluR3,IC50 为 6 μM。 | |||
T70691 |
ITP-2
|
||
ITP-2 is a selective activator of hERG channels. ITP-2 causes large depolarizing shifts in the midpoint of voltage-dependent inactivation and hyperpolarizing shifts in the voltage-dependence of activation. | |||
T70922 |
SKF32802
|
||
SKF32802 is a novel potent, selective hERG potassium channel (Kv11.1) activator that induces a leftward shift in the voltage dependence of activation. | |||
TP1531 |
Guangxitoxin 1E
|
||
Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials. | |||
T80638 |
Glycinexylidide
GX |
MEK | MAPK |
Glycinexylidide (GX) 是一种 Lidocaine 的活性代谢物。作为有效的局部麻醉药,Lidocaine 可以通过阻断复杂电压依赖性的钠通道来发挥作用。此外,它还能抑制胃癌细胞生长、迁移和侵袭。GX 显示出在麻醉、癌症治疗和心血管疾病研究中的应用潜力。 |