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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T2014 CCG-1423

CCG1423

LRRK2; Rho; Ras Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
CCG-1423 是一种选择性 RhoA 通路抑制剂,可抑制 SRF 介导的转录,能抑制细胞的转移前列腺癌PC-3细胞侵袭模型。
T70882 Orlistat-d3

Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...

化合物

CCG-1423
Cat.No: T2014
Synonym: CCG1423
Target: LRRK2, Rho, Ras
Orlistat-d3
Cat.No: T70882
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN3125 5-Methoxycanthin-6-one

Others Others
5-Methoxycanthin-6-one displays moderate cytotoxic activity against the human prostate cancer cell PC-3 line, with IC50 values ranging from 13.5-15.4 uM versus doxorubicine with IC50 = 1.5 uM. It also exhibits a clear suppressive effect on the phagocytosi

天然产物

5-Methoxycanthin-6-one
Cat.No: TN3125
Synonym:
Target: Others
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