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Targets Recommended: TNF

1

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T37445 Etanercept

TNF Apoptosis
Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TNF biologically inactive. Etanercept has demonstrated efficacy in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.

化合物

Etanercept
Cat.No: T37445
Synonym:
Target: TNF
Cat. No. Product Name Species Expression System
TMPK-01382 TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)

p75TNFR,p75TBPII,CD120b,TNF-R75,T...

Cynomolgus HEK293 Cells
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects o...
TMPJ-00618 TNF RII Protein, Rhesus macaque, Recombinant (hFc)

Tnfrsf1b,Tumor necrosis factor receptor superfamily member 1...

Rhesus HEK293 Cells
TNF RII Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-80 KDa and the accession number is F7EAF8.
TMPJ-00296 TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated

Tumor necrosis factor receptor superfamily member 1b,Tnfrsf1...

Mouse HEK293 Cells
TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-50 KDa and the accession number is Q545P4.
TMPY-01697 TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)

Tnfr-1,TNFR80,TNF-R-II,TNF-αR2,tumor necrosis factor recepto...

Mouse HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119.

重组蛋白

TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01382
Species: Cynomolgus
Expression System: HEK293 Cells
TNF RII Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00618
Species: Rhesus
Expression System: HEK293 Cells
TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00296
Species: Mouse
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01697
Species: Mouse
Expression System: HEK293 Cells
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