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3

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T71142	Tebuconazole-d9
	Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per...
T11383	GDP366	Survivin	Apoptosis
	GDP366 有效且特异性地抑制 survivin 和 Op18 的表达。 GDP366 增加染色体不稳定性，并通过抑制端粒酶活性诱导细胞衰老。
T71243	ASP3662
	ASP3662, also known as SPI-62, is a potent, selective and CNS-penetrable inhibitor of 11β-HSD1. The effects of ASP3662 suggest that selective inhibition of 11β-HSD1 may be an attractive approach for the treatment of neuropathic and dysfunctional pain, as observed in fibromyalgia. ASP3662 inhibited human, mouse and rat 11β-HSD1 but not human 11β-HSD2, in vitro. ASP3662 inhibited in vitro conversion of glucocorticoid from its inactive to active form in extracts of rat brain and spinal cord.

化合物

Tebuconazole-d9

Cat.No: T71142

Cat.No: T11383

Target: Survivin

Cat.No: T71243

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00785	ANXA2 Protein, Mouse, Recombinant (His) LIP2PAP-IV,Annexin II,LPC2DP36,LPC2D,CAL1H,Annexin ...	Mouse	E. coli
	ANXA2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 39.6 kDa and the accession number is P07356.
TMPH-03288	EIF3I Protein, Rat, Recombinant (His) eIF3i,Eif3s2,eIF-3-beta,Eukaryotic translation initiation fa...	Rat	Baculovirus Insect Cells
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly an...
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPH-03289	EIF3I Protein, Rat, Recombinant (E. coli, His) eIF3 p36,eIF3i,eIF-3-beta,Eukaryotic translation in...	Rat	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly an...
TMPK-00784	ANXA2 Protein, Human, Recombinant (His) LIP2PAP-IV,LPC2DP36,Annexin II,p36,Annexin...	Human	E. coli
	ANXA2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 39.6 kDa and the accession number is P07355.
TMPJ-00799	ANXA2 Protein, Human, Recombinant ANXA2,Calpactin I Heavy Chain,ANX2,p36,LPC2D,PAP-IV...	Human	E. coli
	Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell...
TMPY-04061	HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) GP36	HIV	E. coli
	HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 58.8 kDa and the accession number is L8B302.
TMPY-01926	S100A10 Protein, Human, Recombinant (His) ANX2L,S100 calcium binding protein A10,p10,CLP11,MGC111133,G...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of int...

重组蛋白

ANXA2 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00785

Species: Mouse

Expression System: E. coli

EIF3I Protein, Rat, Recombinant (His)

Cat.No: TMPH-03288

Species: Rat

Expression System: Baculovirus Insect Cells

NT5C3A/NT5C3 Protein, Human, Recombinant

Cat.No: TMPY-02893

Species: Human

Expression System: E. coli

EIF3I Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03289

Species: Rat

Expression System: E. coli

ANXA2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00784

Species: Human

Expression System: E. coli

ANXA2 Protein, Human, Recombinant

Cat.No: TMPJ-00799

Species: Human

Expression System: E. coli

HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP)

Cat.No: TMPY-04061

Species: HIV

Expression System: E. coli

S100A10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01926

Species: Human

Expression System: E. coli

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