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Cat. No. Product Name Target Signaling Pathways
T3467 Miransertib

ARQ-092,AKT inhibitor 2

Akt; Parasite Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
Miransertib (ARQ-092) 是一种具有口服活性的,选择性和变构性Akt 抑制剂。它有效抑制利什曼原虫,还是 AKT1-E17K 突变蛋白抑制剂,可研究PI3K/AKT 驱动的肿瘤和 Proteus 综合征。
T70152 Miransertib mesylate

Miransertib mesylate is a selective AKT inhibitor that binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K/AKT signaling pathway. This may result in reduction in tumor cell proliferation and the induction of tumor cell apoptosis.
T22247 Miransertib (ARQ 092) HCl

Miransertib hydrochloride (ARQ-092 hydrochloride) is a powerful, orally bioavailable, selective, and allosteric inhibitor of Akt. It exhibits an inhibitory concentration (IC50) of 2.7 nM, 14 nM, and 8.1 nM against Akt1, Akt2, and Akt3, respectively. In addition to its Akt inhibitory activity, Miransertib hydrochloride also demonstrates significant potency as an inhibitor of the AKT1-E17K mutant protein. This compound shows promise in research related to PI3K/AKT-driven tumors and Proteus syndrom...

化合物

Miransertib
Cat.No: T3467
Synonym: ARQ-092,AKT inhibitor 2
Target: Akt, Parasite
Miransertib mesylate
Cat.No: T70152
Synonym:
Target:
Miransertib (ARQ 092) HCl
Cat.No: T22247
Synonym:
Target:
TargetMol Loading
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