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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T4497	Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,阿米吡啶,3,4-Diaminopyridine	Others	Others
	Amifampridine (3,4-Diaminopyridine) 可用于罕见肌肉疾病的研究。
TP1253	Argireline 六胜肽,Acetyl hexapeptide-3,阿基瑞林	Others	Others
	Argireline (Acetyl hexapeptide-3) 是可渗透皮肤的、无毒的抗皱肽。它对神经肌肉接头处依赖 Ca2+的神经递质释放具有显著的抑制作用。它具有抗皱和抗衰老的活性。
T25683	Leucomyosuppressin p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2
	Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
T71758	Ambenonium chloride
	Ambenonium Chloride is the chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereb...
T69158	Ambenonium chloride tetrahydrate
	Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereb...
T73804	Botulinum toxin type B
	Botulinum toxin type B是用于颈部肌张力障碍研究的抗原特异性肉毒毒素。该毒素为厌氧细菌肉毒梭菌产生的外毒素，其机制是通过抑制乙酰胆碱在神经肌肉接头的释放，从而导致注射部位肌肉的松弛性麻痹或减弱。
T75732	α-CGRP, rat TFA
	α-CGRP, rat TFA 是一种神经肽 (降钙素基因相关肽)，主要表达于神经肌肉交界处，是一种有效的血管扩张剂量。α-CGRP, rat TFA 外周给药可使大鼠血压下降、心率升高，并使结肠平滑肌松弛。α-CGRP, rat TFA 可用于心血管、促炎、偏头痛和代谢相关的研究。

化合物

Amifampridine

Cat.No: T4497

Synonym: 3,4-Pyridinediamine,Pyridine-3,4-Diamine,阿米吡啶,3,4-Diaminopyridine

Target: Others

Argireline

Cat.No: TP1253

Synonym: 六胜肽,Acetyl hexapeptide-3,阿基瑞林

Target: Others

Leucomyosuppressin

Cat.No: T25683

Synonym: p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2

Ambenonium chloride tetrahydrate

Cat.No: T69158

Synonym:

Target:

Botulinum toxin type B

Cat. No.	Product Name	Target	Signaling Pathways
T6S0084	Tuberostemonine 对叶百部碱,Tuberstemonine	Parasite	Microbiology/Virology
	Tuberostemonine (Tuberstemonine) 是一种生物碱，可作为抗疟疾剂，有较高的肠道通透性。
T4S1876	3-Deoxyaconitine	Sodium Channel	Membrane transporter/Ion channel
	3-Deoxyaconitine 是一种二萜类生物碱，对钠离子通道有激活作用。
T36068	Brevetoxin B
	Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.