Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79321 |
nSMase2-IN-1
|
Phospholipase | Metabolism |
nSMase2-IN-1是一款口服活性的nSMase2抑制剂,具有0.13 ± 0.06 μM的IC50。该化合物在肝脏微粒体内具有良好的代谢稳定性,口服给药后获得较高的脑血浆比值,适用于神经系统疾病研究。 | |||
T4985 |
Neticonazole Hydrochloride
|
Antifungal | Microbiology/Virology |
Neticonazole hydrochloride 是一种咪唑衍生物,具有抗感染和抗癌作用。它也是一种长效抗真菌剂。 | |||
T69756 |
GT-2331
|
||
GT-2331 is a histamine H3 receptor antagonist. | |||
T69757 |
PDDC inhibitor
|
||
PDDC is the first nSMase2 inhibitor that possesses both favorable pharmacodynamics and pharmacokinetic (PK) parameters, including substantial oral bioavailability, brain penetration, and significant inhibition of exosome release from the brain in vivo. |