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16

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T4509 Inositol nicotinate

Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate

Others Others
Inositol nicotinate (Mesotal) 是一种血管扩张剂,可用于研究外周动脉疾病。
T35938 D-myo-Inositol-4-phosphate (ammonium salt)

D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intr...
T37060 D-myo-Inositol-1,3-diphosphate (sodium salt)

D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in in...
T36069 L-myo-Inositol-1,4,5-triphosphate (sodium salt)

Ins(1,4,5)P3 is an isomer of the biologically important D-myo-inositol-1,4,5-triphosphate. Unlike its isomer, Ins(1,4,5)P3 does not evoke a rise in intracellular calcium when added to cells. It is not known if Ins(1,4,5)P3 can act as a competitive inhibitor of biologically-active inositol phosphates.
T37057 D-myo-Inositol-1,2-diphosphate (sodium salt)

Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2)P2 (te...
T35936 D-myo-Inositol-1,4,6-triphosphate (sodium salt)

D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in int...
T35933 D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt)

D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt),Ins(1,4,5,6)-P4

D-myo-Inositol-1,4,5,6-tetrahosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.[1] D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal tran...
T37058 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)

D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell.
T35935 D-myo-Inositol-1,4,5-triphosphate trisodium

Inositol 1,4,5-trisphosphate trisodium,Ins(1,4,5)-P3 trisodium,D-myo-Inositol-1,4,5-triphosphate (sodium salt),Ins(1,4,5)P3

Calcium Channel Membrane transporter/Ion channel; Metabolism
D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) 是由磷脂酶 C 介导的磷脂酰肌醇-4,5-二磷酸酯水解在细胞中产生的第二信使。D-myo-Inositol-1,4,5-triphosphate (sodium salt)与 Ins(1,4,5)P3受体结合,会导致钙通道的打开和细胞内钙的增加。
T35937 D-myo-Inositol-1,5,6-triphosphate (sodium salt)

The inositol phosphates are a family of mono- to poly-phosphorylated compounds that act as messengers, regulating cellular functions including cell cycling, apoptosis, differentiation, andmotility. D-myo-Inositol-1,5,6-triphosphate is an intermediate compound, produced by the dephosphorylation of various inositol-tetrakisphosphate forms. The triphosphate can be further metabolized to produce inositol-biphosphate mediators. The biological roles of D-myo-inositol-1,5,6-triphosphate remain to be de...
T35934 D-myo-Inositol-1,4,5-triphosphate (potassium salt)

D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium.
T37059 D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)

The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol...
T19266 Ins(1,4,5)-P3 hexapotassium salt

1,4,5-IP3 hexapotassium salt,D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

Others Others
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions.
T77247 D-myo-Inositol 4-monophosphate

D-myo-Inositol 4-mono-phos-phate 是一种生化试剂,可作为生物材料或有机化合物,用于生命科学相关研究。
T83390 2-C-methylene-myo-inositol oxide

NSC 45109

2-C-methylene-myo-inositol oxide (NSC 45109)是一种诱导裂糖酵母假菌丝形成的肌醇衍生物。
T33379 MI 658

MI658,MI-658

MI 658 interferes with the development and induces increased synthesis of myo-inositol synthetase in Neurospora crassa.

化合物

Inositol nicotinate
Cat.No: T4509
Synonym: Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate
Target: Others
D-myo-Inositol-4-phosphate (ammonium salt)
Cat.No: T35938
Synonym:
Target:
D-myo-Inositol-1,3-diphosphate (sodium salt)
Cat.No: T37060
Synonym:
Target:
L-myo-Inositol-1,4,5-triphosphate (sodium salt)
Cat.No: T36069
Synonym:
Target:
D-myo-Inositol-1,2-diphosphate (sodium salt)
Cat.No: T37057
Synonym:
Target:
D-myo-Inositol-1,4,6-triphosphate (sodium salt)
Cat.No: T35936
Synonym:
Target:
D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt)
Cat.No: T35933
Synonym: D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt),Ins(1,4,5,6)-P4
Target:
D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
Cat.No: T37058
Synonym:
Target:
D-myo-Inositol-1,4,5-triphosphate trisodium
Cat.No: T35935
Synonym: Inositol 1,4,5-trisphosphate trisodium,Ins(1,4,5)-P3 trisodium,D-myo-Inositol-1,4,5-triphosphate (sodium salt),Ins(1,4,5)P3
Target: Calcium Channel
D-myo-Inositol-1,5,6-triphosphate (sodium salt)
Cat.No: T35937
Synonym:
Target:
D-myo-Inositol-1,4,5-triphosphate (potassium salt)
Cat.No: T35934
Synonym:
Target:
D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)
Cat.No: T37059
Synonym:
Target:
Ins(1,4,5)-P3 hexapotassium salt
Cat.No: T19266
Synonym: 1,4,5-IP3 hexapotassium salt,D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt
Target: Others
D-myo-Inositol 4-monophosphate
Cat.No: T77247
Synonym:
Target:
2-C-methylene-myo-inositol oxide
Cat.No: T83390
Synonym: NSC 45109
Target:
MI 658
Cat.No: T33379
Synonym: MI658,MI-658
Target:
Cat. No. Product Name Target Signaling Pathways
T0421 i-Inositol

Inositol,myo-Inositol,肌醇,meso-Inositol

Endogenous Metabolite Metabolism
i-Inositol (myo-Inositol) 是一种细胞内磷酸化合物,参与细胞信号传导,可能刺激肿瘤细胞分化。
T2971 Phytic acid

Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid

Xanthine Oxidase; Endogenous Metabolite Metabolism
Phytic acid (Fytic Acid) 是种子和谷粒的磷储存化合物。它被称为食品抑制剂,具有很强的螯合多价金属离子的能力,特别是钙,铁,锌和蛋白质残留物。它抑制超氧化物来源黄嘌呤氧化酶并具有抗氧化,抗炎以及神经保护作用。
TMS0719 Sequoyitol

5-O-Methyl-Myo-Inositol,红杉醇,红杉醇,西曲依醇

Others Others
Sequoyitol (5-O-Methyl-Myo-Inositol) 来源于植物。它可以改善体内葡萄糖耐量,降低血糖,可用于糖尿病的研究。
T16527 Phytic acid dodecasodium salt hydrate

植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate

Others; Xanthine Oxidase; Endogenous Metabolite Metabolism; Others
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶,IC50 为 6 mM,并具有抗氧化、神经保护和抗炎作用。
T5584 Phytic acid sodium salt

Sodium phytate hydrate,玉米

Others Others
Phytic acid sodium salt (Sodium phytate hydrate) 源于豆类种子中,具有抗营养活性。它是 [PO4]3-储藏库,是其他肌醇磷酸酯和焦磷酸酯的前体,在植物中被植酸酶逐步水解。
T5915 D-chiro-Inositol

D-手性肌醇,D-(+)-CHIRO-INOSITOL

Endogenous Metabolite Metabolism
D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) 是肌醇差向异构体,存在于某些哺乳动物糖基磷脂酰肌醇蛋白锚和具有胰岛素样生物特性的肌醇磷脂聚糖中。它能够抑制高血糖,改善胰岛素抵抗。它用于多囊卵巢综合征和糖尿病的相关研究。

天然产物

i-Inositol
Cat.No: T0421
Synonym: Inositol,myo-Inositol,肌醇,meso-Inositol
Target: Endogenous Metabolite
Phytic acid
Cat.No: T2971
Synonym: Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid
Target: Xanthine Oxidase, Endogenous Metabolite
Sequoyitol
Cat.No: TMS0719
Synonym: 5-O-Methyl-Myo-Inositol,红杉醇,红杉醇,西曲依醇
Target: Others
Phytic acid dodecasodium salt hydrate
Cat.No: T16527
Synonym: 植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate
Target: Others, Xanthine Oxidase, Endogenous Metabolite
Phytic acid sodium salt
Cat.No: T5584
Synonym: Sodium phytate hydrate,玉米
Target: Others
D-chiro-Inositol
Cat.No: T5915
Synonym: D-手性肌醇,D-(+)-CHIRO-INOSITOL
Target: Endogenous Metabolite
TargetMol Loading
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