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Cat. No.	Product Name	Target	Signaling Pathways
T10826	CK-666	HIV Protease; Microtubule Associated	Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	CK-666 是一种肌动蛋白相关蛋白 Arp2/3 复合物的细胞渗透性抑制剂。它与 Arp2/3 复合物结合，稳定复合物的非活性状态，阻止 Arp2 和 Arp3 亚基进入活化的丝状短节距构象。
T37952	Sphinganine-1-phosphate (d17:0) Sphinganine-1-phosphate (d17:0)
	Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. Sphinganine-1-phosphate (d17:0) levels are lower in surgical and cadaver trabecular meshwork samples isolated from patients with primary open angle glaucoma compared with control samples.
T37955	Sphingosine-1-phosphate (d16:1) Sphingosine-1-phosphate (d16:1)
	C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples.
T70763	KR-67607
	KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat eyes. KR-67607 showed its protective effects against ischemia-reperfusion-induced eye injury. KR-67607 effectively reduced cortisol levels in mouse eyes and maintained the trabecular meshwork (TM) structure in the presence of transient ischemic stress. Furthermore, KR-67607 rever...
TP2301	type II collagen fragment	Others	Others
	Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primarily type II collagen (z 90–95%), ma
T63637	ROCK-IN-4
	ROCK-IN-4 是 ROCK 的有效抑制剂，可维持 NO 释放能力。ROCK-IN-4 能够可逆地解聚 F-肌动蛋白，并阻碍人小梁网 (HTM) 细胞的线粒体呼吸。ROCK-IN-4 能够用于研究青光眼或高眼压。
TP2182	Lamin fragment	Others	Others
	Lamin fragment has a peptide sequence of Lys-Ala-Gly-Gln-Val-Val-Thr-Ile-Trp. Lamin polypeptides have an almost complete α-helical conformation with multiple α-helical domains separated by non-α-helical linkers that are highly conserved in length and amin