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Targets Recommended: CDK

6

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9734 InhA-IN-2

CDK Cell Cycle/Checkpoint
InhA-IN-2直接抑制 InhA,不需要过氧化氢酶过氧化物酶 KatG 的激活。
T61411 InhA-IN-4

Antibacterial Microbiology/Virology
InhA-IN-4 (TU14) 是一种有效的结核分枝杆菌InhA(烯酰 ACP 还原酶) 抑制剂,具有潜在的抗癌和抗增殖活性,可用于研究结核分枝杆菌感染。
T60866 InhA-IN-3

Antibacterial Microbiology/Virology
InhA-IN-3 (TU13) 是一种有效的结核分枝杆菌InhA(烯酰 ACP 还原酶) 抑制剂,具有潜在的抗癌和抗增殖活性,可用于研究结核分枝杆菌感染。
T73032 MtInhA-IN-1

MtInhA-IN-1是一种口服活性的选择性结核分枝杆菌NADH依赖性烯酰基载体蛋白还原酶(MtInhA)抑制剂,IC50值为0.23 μM。对结核分枝杆菌H37Rv菌株,其MIC为0.4 μM。
T60774 NITD-916

NITD916,NITD 916

Antibiotic Microbiology/Virology
NITD-916 是一种具有口服活性和高度亲脂性的分枝杆菌烯酰还原酶 InhA 抑制剂,IC50 为 570 nM。NITD-916是一种有有效的 4-羟基-2-吡啶酮衍生物, 与 InhA 和 NADH 形成三元复合物,阻止进入脂肪酰基底物结合袋。NITD-916 具有抗结核活性。
T37070 Pyridomycin

Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 μg/ml).

化合物

InhA-IN-2
Cat.No: T9734
Synonym:
Target: CDK
InhA-IN-4
Cat.No: T61411
Synonym:
Target: Antibacterial
InhA-IN-3
Cat.No: T60866
Synonym:
Target: Antibacterial
MtInhA-IN-1
Cat.No: T73032
Synonym:
Target:
NITD-916
Cat.No: T60774
Synonym: NITD916,NITD 916
Target: Antibiotic
Pyridomycin
Cat.No: T37070
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-00272 Inhibin alpha chain/INHA Protein, Bovine, Recombinant (His & SUMO)

Bovine E. coli
Inhibin alpha chain/INHA Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.6 kDa and the accession number is P07994.
TMPH-03008 ENR Protein, Mycobacterium tuberculosis, Recombinant (His)

FAS-II enoyl-ACP reductase,Enoyl-ACP reductase,Enoyl-[acyl-c...

Mycobacterium tuberculosis E. coli
ENR Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.6 kDa and the accession number is P9WGR0.
TMPH-00395 Autolysin Protein, Chlamydomonas reinhardtii, Recombinant (His & SUMO)

Autolysin,GLE,Gametolysin,Gamete lytic enzyme

Chlamydomonas reinhardtii E. coli
Mediates digestion of the cell walls of the 2 mating type gametes during mating as a necessary prelude to cell fusion. This enzyme acts specifically on the framework proteins (inner wall) of the cell wall, cleaving several model peptides at specific sites. Autolysin Protein, Chlamydomonas reinhardtii, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.6 kDa and the accession number is P31178.

重组蛋白

Inhibin alpha chain/INHA Protein, Bovine, Recombinant (His & SUMO)
Cat.No: TMPH-00272
Species: Bovine
Expression System: E. coli
ENR Protein, Mycobacterium tuberculosis, Recombinant (His)
Cat.No: TMPH-03008
Species: Mycobacterium tuberculosis
Expression System: E. coli
Autolysin Protein, Chlamydomonas reinhardtii, Recombinant (His & SUMO)
Cat.No: TMPH-00395
Species: Chlamydomonas reinhardtii
Expression System: E. coli
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