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Cat. No. Product Name Target Signaling Pathways
T7713 Benzyl nicotinate

烟酸苄酯,Rubriment,Pycaril

GPR Endocrinology/Hormones; GPCR/G Protein
Benzyl nicotinate (Pycaril) 是血管扩张剂,可用于引起充血的一种活性成分。
T62036 Sovesudil

Sovesudil (PHP-201) 是有效的、ATP 竞争性局部作用 Rho 激酶(ROCK)抑制剂。Sovesudil 抑制 ROCK I 和 ROCK II 的IC50分别为 3.7 和 2.3 nM。Sovesudil 可以降低眼压而不引起充血。
T71119 Netarsudil free base

Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and​/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Netarsudil inhibited kinases ROCK1 and ROCK2 with a Ki of 1 nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16 nM, respectively, and blocked the profibrotic effects of TGF-β2 in HTM cells. Netarsudi...

化合物

Benzyl nicotinate
Cat.No: T7713
Synonym: 烟酸苄酯,Rubriment,Pycaril
Target: GPR
Sovesudil
Cat.No: T62036
Synonym:
Target:
Netarsudil free base
Cat.No: T71119
Synonym:
Target:
TargetMol Loading
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