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Search Results for " hemagglutinin "

28

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22838	hemagglutinin (332-340) [Influenza A virus]	Others	Others
	Influenza hemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. Influenza hemagglutinin proteins bind to cells w
TP2232	hemagglutinin precursor (114-122) amide [Influenza A virus]	Others	Others
	Partial antigenic glycoprotein
T9231	Mbx2329	Antiviral	Immunology/Inflammation
	MBX2329 是一种流感病毒抑制剂，能特异性地抑制血凝素介导的病毒进入，HIV/HA(H5) 的 IC90值为8.6 μM。它能够有效地抑制多种甲型流感病毒。
T76382	Hemagglutinin (48-68)
	Hemagglutinin (48-68) 为流感病毒血凝素的48至68片段，能够诱导肽特异性T细胞克隆增殖。
T74614	PROTAC Hemagglutinin Degrader-1
	PROTACHemagglutinin Degrader-1 (Compound V3) 是一种有效的 PROTAC 流感病毒血凝素 (influenza hemagglutinin(HA)) 降解剂，降解中值浓度为 1.44 μM。PROTACHemagglutinin Degrader-1 具有广谱抗流感病毒活性。
TP1276	HA Peptide	Others	Others
	HA Peptide 是一种由九个氨基酸组成的多肽，来自于人类流感血凝素 (HA) 。它普遍用于细胞生物学和生物化学中分离，纯化，检测和追踪目标蛋白。
T38719L	Influenza HA (110-119) acetate	Others	Others
	Influenza HA (110-119) acetate 是流感病毒血凝素的 110-119 片段，可刺激 Treg 细胞增殖。
T8793	CBS1117	Influenza Virus	Microbiology/Virology
	CBS1117 是一种病毒进入抑制剂，对甲型流感病毒 A/Puerto Rico/8/34 的 IC50为 70 nM。它干扰血凝素介导的融合过程。
TP1735L	Influenza HA 126-138 acetate Influenza HA 126-138 acetate(207349-63-1 free base)	Others	Others
	Influenza HA 126-138 acetate 是一种流感病毒血凝素 (HA) 肽乙酸盐，包含氨基酸 126-138。它诱导胸腺和外周 T 细胞凋亡。
T26873	BMY-27709 BMY 27709,BMY27709	Influenza Virus	Microbiology/Virology
	BMY-27709 是一种流感病毒生长抑制剂，对 A/WSN/33 病毒生长的 IC50 值为 3-8 μM，对流感病毒的部分亚型也展现出抑制活性。BMY-27709 对 H1 和 H2 病毒感染的早期起作用，通过抑制血凝素蛋白展现其抗病毒活性。然而，BMY-27709 对 H3 亚型病毒以及 B 型/Lee/40 流感病毒没有作用。
T68454	IAV inhibitor 4l
	IAV inhibitor 4l is an IAV inhibitor targeting hemagglutinin and mediates viral entry by preventing HA-membrane fusion.
TP1854	Influenza HA (307-319) Influenza HA 307-319
	Influenza Hemagglutinin is an HLA-DRB 0101-restricted epitope from influenza hemagglutinin (307-319).
T27610	Ingavirin
	Ingavirin, a novel inhibitor of the influenza virus reproduction, inhubits the formation of the virus specific hemagglutinin.
T77021	Gedivumab
	Gedivumab (MHAA4549A; RG7745)，一种高特异性人源单克隆抗体，靶向甲型流感病毒 (IAV)，通过与IAV血凝素蛋白的高度保守茎区结合，阻止其成熟并阻断核内体中的血凝素介导的膜融合，适用于IAV感染疾病研究。
T62216	Influenza virus-IN-5
	Influenza virus-IN-5 (Compound 5f) 是一种流感病毒血球凝集素 (hemagglutinin (HA)) 抑制剂，能够作用于 A/H3N2 病毒 (EC50: 1 nM)。
T15625	JNJ4796	Others	Others
	JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).
T10281	Alimemazine Trimeprazine	Others	Others
	Alimemazine (Trimeprazine) is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Alimemazine also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs.
T38719	Influenza HA (110-119)
	Influenza HA (110-119) refers to a specific fragment (110-119) derived from the hemagglutinin protein of the influenza virus. This fragment has the ability to induce the proliferation of Treg cells.
TP1735	Influenza HA (126-138) Influenza HA 126-138
	Influenza HA (126-138) is a peptide derived from the hemagglutinin (HA) protein of the influenza virus. It consists of amino acids 126-138 and has the ability to induce apoptosis in both thymic and peripheral T-cells.
T37466	CAY10766
	CAY10766 is an antiviral compound.1It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50= 0.24 μM). CAY10766 (1 μM) reduces H1N1 and H5N1 influenza A viral titers in infected MDCK cells. It also exhibits synergy with oseltamivir carboxylate in MDCK cells infected with the influenza A reporter PR8-NS1-Gluc virus.
T68413	CBS1194
	CBS1194 is a novel antiviral agent against influenza A virus (IAV), and is more specifically, a group 2 IAV fusion inhibitor. CBS1194 prevents membrane fusion of the virus through the inhibition of the conformational change of hemagglutinin (HA). CBS1194 causes steric hinderance that prevents the rearrangement of the HA that would normally be induced by low-pH, by fitting into the pocket by the fusion peptide.
T77094	Navivumab
	Navivumab (CT-P23)是针对甲型流感病毒(influenza A virus) HA血凝素的单克隆抗体。该药物通过结合HA2蛋白的茎融合结构域，能中和H1、H2、H5及H9型甲型流感病毒。
T81037	Tat-HA-NR2B9c
	Tat-HA-NR2B9 是一种包括HIV-1 Tat细胞膜转导结构域片段、流感病毒血凝素(HA)表位标签以及NR2B(NR2B9c) C端9个氨基酸的化学复合物。该化合物能够降低大鼠缺血性脑损伤的梗塞面积，同时促进神经功能的恢复。
T69398	LUN15104
	LUN15104 is a novel hemagglutinin (HA) protein inhibitor, inhibiting entry and replication of diverse influenza viruses via the HA protein, showing potent antiviral activity against diverse H1N1, H5N1, and H3N2 influenza viruses encoding HA proteins from both groups 1 and 2. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKo...
T79444	HA-IN-1	Influenza Virus	Microbiology/Virology
	HA-IN-1（compound 5g）是靶向血凝素（HA）胰蛋白酶切割位点的配体，表现出高亲和力。该化合物能够抑制HA介导的膜融合，并在体内有效降低肺部病毒滴度，展现其作为甲型流感病毒（IAV）抑制剂和抗流感药物的潜力。
T80279	Urumin	Influenza Virus	Microbiology/Virology
	Urumin 对人类甲型流感病毒显示出抗病毒活性，通过靶向 H1 血凝素的保守茎部位，能有效中和耐药 H1 流感病毒。它在抑制 PR8 流感病毒的生长中的半抑制浓度（IC50）为 3.8 μM，并能保护幼鼠免遭致命流感病毒感染。
T77009	Firivumab
	Firivumab (CT-P22; CT120)是一种针对人类IgG1单克隆的抗甲型流感病毒血凝素（Anti-IAV HA）抗体。该抗体能有效中和多种亚型，包括H1N1、H5N1、H6N1、H6N2、H8N4、H8N8、H9N2和H12N7。研究发现，Firivumab在小鼠模型中对H1N1病毒展现出显著的保护效果。
T37347	6'-Sialyllactose Sodium Salt 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose
	6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne...

化合物

hemagglutinin (332-340) [Influenza A virus]

Cat.No: T22838

Target: Others

hemagglutinin precursor (114-122) amide [Influenza A virus]

Cat.No: TP2232

Target: Others

Cat.No: T9231

Target: Antiviral

Hemagglutinin (48-68)

Cat.No: T76382

PROTAC Hemagglutinin Degrader-1

Cat.No: T74614

Cat.No: TP1276

Target: Others

Influenza HA (110-119) acetate

Cat.No: T38719L

Target: Others

Cat.No: T8793

Target: Influenza Virus

Influenza HA 126-138 acetate

Cat.No: TP1735L

Synonym: Influenza HA 126-138 acetate(207349-63-1 free base)

Target: Others

Cat.No: T26873

Synonym: BMY 27709,BMY27709

Target: Influenza Virus

IAV inhibitor 4l

Cat.No: T68454

Influenza HA (307-319)

Cat.No: TP1854

Synonym: Influenza HA 307-319

Cat.No: T27610

Cat.No: T77021

Influenza virus-IN-5

Cat.No: T62216

Cat.No: T15625

Target: Others

Cat.No: T10281

Synonym: Trimeprazine

Target: Others

Influenza HA (110-119)

Cat.No: T38719

Influenza HA (126-138)

Cat.No: TP1735

Synonym: Influenza HA 126-138

Cat.No: T37466

Cat.No: T68413

Cat.No: T77094

Cat.No: T81037

Cat.No: T69398

Cat.No: T79444

Target: Influenza Virus

Cat.No: T80279

Target: Influenza Virus

Cat.No: T77009

6'-Sialyllactose Sodium Salt

Cat.No: T37347

Synonym: 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose

Cat. No.	Product Name	Target	Signaling Pathways
T13818	Phytohemagglutinin PHA-M,植物血球凝集素,PHA,植物血凝素	Apoptosis	Apoptosis
	Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素，聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂，能够刺激人单核白细胞，可诱导 ChAT mRNA 表达，增强 ACh 合成。
T78491	Phytohemagglutinin P PHA-P
	Phytohemagglutinin P（PHA-P）是一类植物凝集素，以选择性方式激活血源性或淋巴样单核细胞的有丝分裂。
T19719	TBMP butylated hydroxyanisole	Others	Others
	TBMP (butylated hydroxyanisole) 是病毒包膜蛋白血凝素 (HA) 介导的进入新型抑制剂。
T75743	HA Peptide TFA
	HA Peptide (TFA) 为源自人类流感血凝素 (HA) 的九氨基酸多肽，在细胞生物学与生物化学领域内广泛应用于目标蛋白的分离、纯化、检测及追踪。
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...

天然产物

Phytohemagglutinin

Cat.No: T13818

Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素

Target: Apoptosis

Phytohemagglutinin P

Cat.No: T78491

Synonym: PHA-P

Cat.No: T19719

Synonym: butylated hydroxyanisole

Target: Others

Cat.No: T75743

9(S),12(S),13(S)-TriHOME

Cat.No: T37272

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