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Cat. No. Product Name Target Signaling Pathways
T2681 hPGDS-IN-1

PGE Synthase Immunology/Inflammation
hPGDS-IN-1hPGDS 抑制剂,使用荧光偏振检测或通过 EIA 法测得的 IC50值为12 nM。
T1804 HPGDS inhibitor 1

HPGDS-inhibitor-1

PGE Synthase Immunology/Inflammation
HPGDS inhibitor 1 是口服具有活性的HPGDS 选择性抑制剂,在酶和细胞分析中的IC50值分别为 0.6 nM 和 32 nM,但对 L-PGDS、mPGES、COX-1、COX-2 、5-LOX 无抑制作用。
T61250 HPGDS inhibitor 3

HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally restricting H-PGDS. Moreover, HPGDS inhibitor 3 exhibits excellent selectivity with no associated central nervous system toxicity. This compound also possesses favorable pharmacokinetic properties in mouse, rat, and dog models. Additionally, HPGDS inhibitor 3 displays noteworthy an...

化合物

hPGDS-IN-1
Cat.No: T2681
Synonym:
Target: PGE Synthase
HPGDS inhibitor 1
Cat.No: T1804
Synonym: HPGDS-inhibitor-1
Target: PGE Synthase
HPGDS inhibitor 3
Cat.No: T61250
Synonym:
Target:
TargetMol Loading
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