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Cat. No. Product Name Target Signaling Pathways
T16276 NBD-556

HIV Protease Microbiology/Virology; Proteases/Proteasome
NBD-556是一种 CD4 模拟物,识别 HIV-1 包膜蛋白 gp120 并诱导 gp120 重组,类似于 CD4 结合,可阻断 gp120-CD4 的相互作用。
T6418 BMS-378806

BMS378806,BMS-806,1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-B]吡啶-3-基)-1,2-乙二酮

gp120/CD4; HIV Protease Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
BMS-378806 (BMS-806) 是一种 HIV-1 抑制剂,可选择性抑制 HIV-1 gp120 结合到 CD4 受体,EC50为 0.85-26.5 nM。
T4665 Temsavir

BMS626529

HIV Protease Microbiology/Virology; Proteases/Proteasome
Temsavir (BMS626529) 是一种新型附着抑制剂,靶向 HIV-1 gp120 并阻止其与 CD4+ T 细胞结合。
TP1785L Peptide T acetate(106362-32-7 free base)

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Peptide T acetate(106362-32-7 free base) 是一种来自 HIV-1 gp120 V2 区域的八肽。它是一种合成八肽,其可能的作用机制是 gp120CD4 受体的竞争性抑制以及与血管肠肽受体的结合和抑制细胞因子作用。
T10570 Fostemsavir Tris

BMS-663068 Tris

HIV Protease Microbiology/Virology; Proteases/Proteasome
Fostemsavir Tris (BMS-663068 Tris) 是一种 HIV-1附着抑制剂。
T3523 Fostemsavir

BMS-663068,磷坦姆沙韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Fostemsavir (BMS-663068) 是 BMS-626529 的原药,可抑制 HIV-1 与细胞 CD4 受体的结合,能结合gp120
T72099 Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl

Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl (化合物 (CPF(LL)) 是一种 HIV-1抑制剂。Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl 能与 gp120相互作用以阻断 gp120CD4的结合,并保留 CD4依赖的 T 细胞功能。
T69371 BMS 378806

BMS-378806 is an orally bioavailable HIV-1 inhibitor that interferes with gp120-CD4 interaction.
T71094 CD4 (81-92)

CD4 (81-92) is a peptide that was previously found to inhibit gp120 binding, HIV-1 infectivity, and syncytium formation.
TP1873 Peptide T TFA

Peptide T (TFA) is an octapeptide derived from the V2 region of HIV-1 gp120. It serves as a ligand for the CD4 receptor, effectively inhibiting the binding of HIV to the CD4 receptor.
TP1785 Peptide T

Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and in
T81295 Retrocyclin-1

Retrocyclin-1是一种θ防御素,具有识别并结合含碳水化合物表面分子的能力,能够保护细胞抵御HIV-1感染。该化合物对胎球蛋白、gp120(Kd=35.4 nM)、CD4(Kd=31 nM)以及半乳糖神经酰胺(Kd=24.1 nM)展现出高度亲和性。
T68842 Complestatin

Complestatin is a compound extracted from Streptomyces lavendulae mycelia; on acid hydrolysis yields D-4-hydroxyphenylglycine & D-3,5-dichloro-4-hydroxyphenylglycine & acidic chromophore; inhibits gp120-CD4 binding. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. It has a role as a metabolite, an antimicrobial agent and an anti-HIV-1 agent.
T37874 Feglymycin

Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replication in H9 cells (IC50 = ~5 μM). Feglymycin is also active against clinical isolates of HIV-1 from clades A-D, A/E, and G (EC50s = 0.5-6.7 μM). It interacts with gp120 and inhibits HIV-1 NL4.3 binding to human soluble CD4 (EC50 = 4.4 μM) and to CD4+ SupT1 T cells by 74.5% when us...
T77792 HIV Peptide T

HIV Peptide T(Peptide T),这种合成的八肽是HIV感染治疗中的一种抗病毒药物,其主要通过竞争性抑制gp120(HIV表面蛋白)与CD4受体的相互作用,同时与血管肠肽(vasointestinal peptide, VIP)受体同源结合并且阻断细胞因子的产生与作用来发挥功效。
T38103 Defensin HNP-3 (human) (trifluoroacetate salt)

Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd...

化合物

NBD-556
Cat.No: T16276
Synonym:
Target: HIV Protease
BMS-378806
Cat.No: T6418
Synonym: BMS378806,BMS-806,1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-B]吡啶-3-基)-1,2-乙二酮
Target: gp120/CD4, HIV Protease
Temsavir
Cat.No: T4665
Synonym: BMS626529
Target: HIV Protease
Peptide T acetate(106362-32-7 free base)
Cat.No: TP1785L
Synonym:
Target: Others, HIV Protease
Fostemsavir Tris
Cat.No: T10570
Synonym: BMS-663068 Tris
Target: HIV Protease
Fostemsavir
Cat.No: T3523
Synonym: BMS-663068,磷坦姆沙韦
Target: HIV Protease
Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl
Cat.No: T72099
Synonym:
Target:
BMS 378806
Cat.No: T69371
Synonym:
Target:
CD4 (81-92)
Cat.No: T71094
Synonym:
Target:
Peptide T TFA
Cat.No: TP1873
Synonym:
Target:
Peptide T
Cat.No: TP1785
Synonym:
Target:
Retrocyclin-1
Cat.No: T81295
Synonym:
Target:
Complestatin
Cat.No: T68842
Synonym:
Target:
Feglymycin
Cat.No: T37874
Synonym:
Target:
HIV Peptide T
Cat.No: T77792
Synonym:
Target:
Defensin HNP-3 (human) (trifluoroacetate salt)
Cat.No: T38103
Synonym:
Target:
TargetMol Loading
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