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25

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T18883	2-Di-1-ASP	Others	Others
	2-Di-1-ASP 是单苯乙烯基染料，对 G-四链体和双链 DNA 具有选择性。它普遍用作双链 DNA 的线粒体染色和凹槽结合荧光探针。
T4065	Fluorescein Sodium 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001	Others	Others
	Fluorescein Sodium (VST-1001) 是一种具有代表性的绿色荧光示踪剂，广泛用于医学、生物应用和肿瘤感染组织的示踪剂，也可作为实用绿色荧光探针的支架。
T77674	3-Cyano-7-hydroxycoumarin 3-Cyanoumbelliferone
	3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) 是一种巨噬细胞游走抑制因子 (MIF) 互变异构酶抑制剂，Ki 为 2.9 μM。3-Cyano-7-hydroxycoumarin 属于香豆素衍生物，可被用作分子探针和荧光染料。
T66518	BODIPY-FL BDP FL acid
	BODIPY-FL (BDP FL acid) 是一种广谱且有效的荧光染料，可用于标记探针或引物，是一种基于荧光猝灭的定量检测特定 DNA/RNA 的化合物。BODIPY-FL 标记的单萜可用于检测革兰氏阳性和革兰氏阴性细菌的特征和致病真菌。
T19078	(±)-ANAP	Others	Others
	(±)-ANAP is the amino acid analog of prodan. It can be used as a fluorescent probes and enhance environmental sensitivity.
T19079	(±)-ANAP hydrochloride (1185251-08-4 free base) (±)-ANAP hydrochloride	Others	Others
	(±)-ANAP hydrochloride is the amino acid analog of prodan. It can be used as a fluorescent probes and enhance environmental sensitivity.
T39096	ICG-OSu ICG NHS ester,ICG-OSu
	ICG-OSu, also known as ICG NHS ester, is a near-infrared fluorescent agent commonly utilized for the development of in vivo imaging probes due to its amine-reactive properties.
T38600	N-ε-propargyloxycarbonyl-L-lysine N-ε-propargyloxycarbonyl-L-lysine,H-?L-?Lys(Poc)?-?OH
	N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is an unnatural amino acid (UAA) derived from lysine. It is commonly employed for bio-conjugation purposes, specifically for attaching fluorescent probes in a variety of organisms ranging from E. coli to mammalian cells, including animals.
TD0053	Fluo-3, pentapotassium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentapotassium salt is most commonly used among the visible light-excitable calcium indicators.
T39432	HKOCl-4 HKOCl-4,BXY2142
	HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluorescein-based probes, and it exhibits better pH stability. Notably, HKOCl-4 exhibits excitation at 530 nm and emission at 557 nm.
T80214	cRGDfK-thioacetyl ester	Integrin	Cytoskeletal Signaling
	cRGDfK-thioacetyl ester 为具选择性亲和力于整合素（integrins）之生物活性多肽。可应用于修饰NIR荧光探针，实现癌症靶向成像。
TD0052	Fluo-3, pentasodium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentasodium salt is most commonly used among the visible light-excitable calcium indicators.
TD0054	Fluo-3, pentaammonium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentaammonium salt is most commonly used among the visible light-excitable calcium indicators.
T75269	DMT-5Me-dC(Bz)-CE Phosphoramidite
	DMT-5Me-dC(Bz)-CE Phosphoramidite 用于生产锁定核酸（LNAs），旨在优化荧光寡核苷酸探针的设计，从而提升其光谱性质和对目标的结合能力。
T37045	1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose
	1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block.1,2It has been used as a precursor in the synthesis of differently substituted trimers of the group AN. meningitidiscapsular polysaccharide repeating unit for use in immunological experiments.2It has also been used in the synthesis of fluorescent probes for lysosomal labeling.3
TD0055	Fluo-8, AM
	Fluo-8,AM is one of the most commonly used fluorescent probes to detect intracellular calcium concentration.Fluo-8, which penetrates the cell membrane and enters the cell, is cut by the intracellular esterase to form fluO-8, and thus is trapped in the cel
TD0051	Fluo-4, pentaammonium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentaammonium salt is an analog of fluo-3 with the...
T37095	Quin-2 (potassium salt)
	Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium). It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 an...
TD0050	Fluo-4, pentapotassium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentapotassium salt is an analog of fluo-3 with th...
TD0049	Fluo-4, pentasodium salt
	Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentasodium salt is an analog of fluo-3 with the t...
T30783	CDy9 CDy 9,CDy-9
	CDy9 is a highly selective fluorescent probe for the detection and isolation of mESC using fluorescence microscopy and flow cytometry. CDy9 allows the detection and isolation of intact stem cells with marginal impact on their function and capabilities. CD
T36502	DCP-Rho1 DCP-Rho1
	DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in situ. \|1. Klomsiri, C., Rogers, L.C., Soito, L., et al. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Rad. Biol. Med. 71, 49-60 (2014).\|2. Holmila, R.J., Vance, S.A., Chen, X., et ...
T38382	8Br-HA
	8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively). 1.Kawaguchi, M., Sekimoto, E., Ohta, Y., et al.Synthesis of fluorescent probes targeting tumor-suppressor protein FHIT and Identification of apoptosis-inducing FHIT inhibitorsJ. Med. Chem.64(13)9567-9576(2021)
T37049	monoMICAAc
	monoMICAAc is a solvatochromic fluorescent pH probe.1 As the polarity of the solvent increases, the emission wavelength of monoMICAAc increases. It displays excitation/emission maxima of 425/491, 437/515, and 472/554 nm in hexane, dioxane, and water, respectively. The absorption maximum of monoMICAAc decreases with increasing pH. It displays absorbance/emission maxima of 475/553 and 446/553 nm at pH 3 and 11, respectively, in aqueous Britton-Robinson buffer, and the fluorescence intensity increa...
T36843	ICAAc
	ICAAc is a solvatochromic fluorescent pH probe.1 As the polarity of the solvent increases, the emission wavelength of ICAAc increases. It displays excitation/emission maxima of 466/553, 431/515, and 418/503 nm in water, dioxane, and hexane, respectively. The absorption maximum of ICAAc decreases with increasing pH. It displays absorption/emission maxima of 470/554 and 428/553 nm at pH 3 and 11, respectively, in aqueous Britton-Robinson buffer, and the fluorescence intensity increases as pH decre...

化合物

Cat.No: T18883

Target: Others

Fluorescein Sodium

Cat.No: T4065

Synonym: 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001

Target: Others

3-Cyano-7-hydroxycoumarin

Cat.No: T77674

Synonym: 3-Cyanoumbelliferone

Cat.No: T66518

Synonym: BDP FL acid

Cat.No: T19078

Target: Others

(±)-ANAP hydrochloride (1185251-08-4 free base)

Cat.No: T19079

Synonym: (±)-ANAP hydrochloride

Target: Others

Cat.No: T39096

Synonym: ICG NHS ester,ICG-OSu

N-ε-propargyloxycarbonyl-L-lysine

Cat.No: T38600

Synonym: N-ε-propargyloxycarbonyl-L-lysine,H-?L-?Lys(Poc)?-?OH

Fluo-3, pentapotassium salt

Cat.No: TD0053

Cat.No: T39432

Synonym: HKOCl-4,BXY2142

cRGDfK-thioacetyl ester

Cat.No: T80214

Target: Integrin

Fluo-3, pentasodium salt

Cat.No: TD0052

Fluo-3, pentaammonium salt

Cat.No: TD0054

DMT-5Me-dC(Bz)-CE Phosphoramidite

Cat.No: T75269

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

Cat.No: T37045

Cat.No: TD0055

Fluo-4, pentaammonium salt

Cat.No: TD0051

Quin-2 (potassium salt)

Cat.No: T37095

Fluo-4, pentapotassium salt

Cat.No: TD0050

Fluo-4, pentasodium salt

Cat.No: TD0049

Cat.No: T30783

Synonym: CDy 9,CDy-9

Cat.No: T36502

Synonym: DCP-Rho1

Cat.No: T38382

Cat.No: T37049

Cat.No: T36843

Cat. No.	Product Name	Target	Signaling Pathways
T7977	Benzofuroxan	Others	Others
	Benzofuroxan 被用作合成其他化合物的起始材料，如药物和其他化学品；也用于聚合物的合成；还被用于合成荧光染料，并作为检测某些分子的荧光探针。

天然产物

Cat.No: T7977

Target: Others

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