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Cat. No.	Product Name	Target	Signaling Pathways
T38776	LP-922056	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	LP-922056 是 Notum Pectinacetylesterase 的抑制剂，对人和小鼠的 EC50 值分别为 21 nM 和 55 nM。
T35676	17β-hydroxy Exemestane
	17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (IC50 = 69 nM using human placental microsomes) and an androgen receptor (AR) agonist (IC50 = 39.6 nM) that is selective for AR over estrogen receptor α (ERα; IC50 = 21.2 μM). It stimulates growth of AR- and ERα-positive MCF-7 (EC50 = 2.7 μM) and T47D breast cancer cells (EC50s = ...