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抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
TP1187 C-Type Natriuretic Peptide (CNP) (1-22), human

CNP (1-22), human

RAAS Endocrinology/Hormones
C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂,是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。
T29809 AL-1

AL 1,AL1

AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variety of adult tissues of BRAIN; HEART;

化合物

C-Type Natriuretic Peptide (CNP) (1-22), human
Cat.No: TP1187
Synonym: CNP (1-22), human
Target: RAAS
AL-1
Cat.No: T29809
Synonym: AL 1,AL1
Target:
Cat. No. Product Name Target Signaling Pathways
TN2977 3-O-trans-p-Coumaroyltormentic acid

Caspase; Antifection Apoptosis; Microbiology/Virology; Proteases/Proteasome
3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3beta-O-cis-p-Coumaroyltormentic acid, an...

天然产物

3-O-trans-p-Coumaroyltormentic acid
Cat.No: TN2977
Synonym:
Target: Caspase, Antifection
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