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Cat. No. Product Name Target Signaling Pathways
T77580 IK-930

compound I-32

YAP Stem Cells
IK-930 是一种具有口服活性 TEAD 抑制剂(EC50 < 0.1 µM)具有强效性。
T79648 CDK2-IN-19

CDK Cell Cycle/Checkpoint
CDK2-IN-19 (Compound 32)为一种口服活性的选择性CDK2抑制剂(Ki:0.18 nM),在带OVCAR3肿瘤的小鼠模型中表现出显著的抗癌效果。
T36865 Heat Shock Protein Inhibitor II

Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of A...

化合物

IK-930
Cat.No: T77580
Synonym: compound I-32
Target: YAP
CDK2-IN-19
Cat.No: T79648
Synonym:
Target: CDK
Heat Shock Protein Inhibitor II
Cat.No: T36865
Synonym:
Target:
TargetMol Loading
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