3
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12006 |
Metarrestin
ML246 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Metarrestin (ML246) 是一种口服有效的选择性核仁周区室 (PNC) 抑制剂,可有效抑制转移。Metarrestin 破坏核仁结构并抑制 RNA 聚合酶 (Pol) I 转录,部分是通过与翻译延伸因子 eEF1A2 的相互作用。 | |||
T16875 |
SF1126
|
Others | Others |
SF1126 is a relevant pan and dual first-in-class PI3K/BRD4 inhibitor. SF1126 is an RGDS-conjugated LY294002 prodrug, which is designed to exhibit increased solubility and bind to specific integrins within the tumor compartment. | |||
T71525 |
AB05831
|
||
AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis of terminal, non-reducing N-acetyl-|3-D-glucosamine (GlcNAc) andN-acetyl-(3-D-galactosamine (GalNAc) residues in glycoproteins, gan-gliosides, and glycosaminoglycans (GAGs). HEX, released by chondrocytes into the extracellular compartment, promotes cartilage matrix degradation. ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3875 |
CLINODISIDE A
|
Others | Others |
Clinodiside A 是来自中草药Clinopodium chinensis 中。 |