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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T79088	Chlamydia pneumoniae-IN-1
	Chlamydia pneumoniae-IN-1 (compound 55)，一种抗衣原体的苯并咪唑类化合物，对肺炎衣原体具有高度抑制作用，在10 μM 浓度下能够抑制99%的肺炎衣原体生长，并对宿主细胞的活力产生95%的抑制效果。此外，Chlamydia pneumoniae-IN-1 对CV-6菌株亦显示出明显的抗菌活性，其最小抑菌浓度(MIC)为12.6 μM。
T7865	Danofloxacin 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine	Others; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
T60092	CHEMBL1276927 N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide,N-[3-(1H-苯并[d]咪唑-2-基)苯基]-3-甲基苯甲酰胺	Antibacterial; Parasite	Microbiology/Virology
	CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) 对肺炎衣原体和多诺瓦尼利什曼原虫具有抗菌和抗寄生虫活性。
T27751	KSK-120 KSK120,KSK 120
	KSK-120 is a potent Chlamydia trachomatis inhibitor, it targets the glucose-6-phosphate (G-6P) metabolism pathway of Chlamydia trachomatis.
TP2107	TAPI 0
	ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
T70103	KSK213
	KSK213 is a potent inhibitor of Chlamydia trachomatis Infectivity (EC50 = 60 nM). KSK213 potently inhibited multiple serovars of C. trachomatis while not affecting the growth of key species from the commensal flora or host cell viability at 25 μM.
T73532	JO146
	JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂，其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM，可应用于细菌感染的抑制。

化合物

Chlamydia pneumoniae-IN-1

Synonym: 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine

Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic

CHEMBL1276927

Cat.No: T60092

Synonym: N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide,N-[3-(1H-苯并[d]咪唑-2-基)苯基]-3-甲基苯甲酰胺

Target: Antibacterial, Parasite

KSK-120

Cat.No: T27751

Synonym: KSK120,KSK 120

Cat. No.	Product Name	Target	Signaling Pathways
T1304	Chlortetracycline hydrochloride Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Chlortetracycline hydrochloride (Isphamycin) 是一种特异性钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。