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Search Results for " ceramide glucosyltransferase "

抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0155	Miglustat hydrochloride NB-DNJ hydrochloride,盐酸美格鲁特,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride	Transferase	Metabolism
	Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) 是一种葡萄糖神经酰胺合酶抑制剂，可用于 I 型戈谢病的相关研究。
T35626	AMP-Deoxynojirimycin AMP-DNM	Transferase; Glucosidase	Metabolism
	AMP-Deoxynojirimycin (AMP-DNM) 是一种有效的神经酰胺葡萄糖基转移酶和 GCase 2 抑制剂。AMP-Deoxynojirimycin 是一种有效的 GlcCer 生物合成抑制剂，可用于研究帕金森和糖尿病。
T4473	Ibiglustat Venglustat,SAR402671,GZ402671	Transferase	Metabolism
	Ibiglustat (GZ402671) 是一种可透过血脑屏障的、具有口服活性的葡萄糖神经酰胺合成酶(GCS)抑制剂。它可用于戈谢病 3 型、法布瑞氏症、与 GBA 突变相关的帕金森病、GM2 神经节苷脂病和常染色体显性多囊肾病的研究。
T70347	Ibiglustat hydrochloride
	Ibiglustat hydrochloride is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor.
T36319	C6 L-erythro Ceramide (d18:1/6:0) C6 L-erythro Ceramide (d18:1/6:0)
	C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).
T38489	D,L-erythro-PDMP
	D,L-erythro-PDMP, an erythro isomer of PDMP, exhibits growth inhibition on cultured rabbit skin fibroblasts. Additionally, this compound serves as an effective inhibitor of UDP-glucose: ceramide glucosyltransferase.
T36320	C6 L-threo Ceramide (d18:1/6:0) C6 L-threo Ceramide (d18:1/6:0)
	C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.
T37565	C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide (d18:1/6:0)
	C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater...
T70336	Nizubaglustat
	Nizubaglustat为一种针对神经酰胺葡萄糖基转移酶或葡萄糖神经酰胺合酶(GCS)的抑制剂，同时也能抑制GBA2，后者与神经病理学溶酶体贮积症相关。

化合物

Miglustat hydrochloride

Cat.No: TQ0155

Synonym: NB-DNJ hydrochloride,盐酸美格鲁特,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride

Target: Transferase

AMP-Deoxynojirimycin

Cat.No: T35626

Synonym: AMP-DNM

Target: Transferase, Glucosidase

Ibiglustat

Cat.No: T4473

Synonym: Venglustat,SAR402671,GZ402671

Target: Transferase

Ibiglustat hydrochloride

Cat.No: T70347

Synonym:

Target:

C6 L-erythro Ceramide (d18:1/6:0)

Cat.No: T36319

Synonym: C6 L-erythro Ceramide (d18:1/6:0)

C6 L-threo Ceramide (d18:1/6:0)

Cat.No: T36320

Synonym: C6 L-threo Ceramide (d18:1/6:0)

Target:

C6 D-threo Ceramide (d18:1/6:0)

Cat.No: T37565

Synonym: C6 D-threo Ceramide (d18:1/6:0)

Cat. No.	Product Name	Target	Signaling Pathways
T12039	Miglustat N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素	Others	Others
	Miglustat (NB-DNJ) 是一种葡萄糖神经酰胺合成酶抑制剂，可用于I 型戈谢病。

天然产物

Miglustat

Cat.No: T12039

Synonym: N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素

Target: Others

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