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Cat. No.	Product Name	Target	Signaling Pathways
T6428	BV6	IAP	Apoptosis
	BV6 是 c-IAP1 和 XIAP 的拮抗剂，它们是凋亡抑制剂 (IAP) 家族的成员。
T36317	SM-1295
	SM-1295 serves as an antagonist to the inhibitor of apoptosis protein (IAP), demonstrating dissociation constant (Kd) values of 3077 nM for XIAP-BIR3, 3.2 nM for c-IAP1-BIR3, and 9.5 nM for c-IAP2-BIR3, respectively[1][2].
T70096	AEG40730 HCl
	AEG40730 is a potent and selective IAP antagonist and a BIR-binding tetrapeptide. AEG40730 binds to cIAP1 and cIAP2, facilitates their autoubiquitination and proteosomal degradation, and causes a dramatic reduction in RIP1 ubiquitination. Treatment with nanomolar concentrations of AEG40730 resulted in the loss of both XIAP and c-IAP1 proteins, albeit with different kinetics.