Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22428 |
Sodium Glucoheptonate
Sodium glucoheptonate,葡萄醣庚酸钠 |
Others | Others |
Sodium Glucoheptonate (Sodium glucoheptonate) 可用作 Tc-99m 放射性标记的试剂盒,也可用于清洗金属、丝光、脱漆和铝蚀刻。其中Tc-99m glucoheptonate 是一种肾脏和脑部成像剂,可用于检测脑肿瘤。 | |||
T31091 |
CRANAD-28
CRANAD28 |
Others | Others |
CRANAD-28 是一种血脑屏障(BBB)穿透型双光子成像探头,能够显示淀粉样蛋白斑块,可以标记斑块和脑淀粉样血管病。 | |||
T63540 |
Astrophloxine
|
Beta Amyloid | Neuroscience |
Astrophloxine 是一种荧光成像探针,靶向反平行二聚体。Astrophloxine 能够用于检测阿尔茨海默症 (AD) 小鼠脑组织和脑脊液样本中聚集的 Aβ。 | |||
T15162 |
DPA-714
|
Others | Others |
DPA-714 是高亲和力的移位蛋白配体 (Ki=7 nM),它结构中有一个氟原子,能够被氟 -18 进行标记,并可通过正电子发射断层成像进行活体成像。它可在各种神经炎症模型及脑肿瘤模型中成功评估炎症的特异性成像。 | |||
T34688 |
SP203
SP-203,SP 203 |
||
SP203 is a radioligand for brain metabotropic glutamate receptor imaging. | |||
T31389 |
Desmethyl-HD-800
Desmethyl-HD800,Desmethyl HD800 |
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Desmethyl-HD-800 is a PET precursor of preparing radiolabel [11C]HD-800, a high affinity brain penetrant PET tracer for imaging microtubules. | |||
T83130 |
AMCPy
|
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AMCPy 是一款有效的 EPR 脑成像剂,其优秀的亲脂性使其能够穿透 BBB。 | |||
T22428L |
Sodium Glucoheptonate Dihydrate
|
Others | Others |
Sodium glucoheptonate dihydrate 作为 Tc-99m 放射性标记试剂盒提供。 Tc-99m glucoheptonate 是一种用于脑肿瘤检测的肾和脑成像剂。 | |||
T75145 | TRV-7019 | ||
TRV-7019,一种能穿透血脑屏障的放射性配体,用于丁酰胆碱酯酶的脑成像,适用于淀粉样蛋白病、多发性硬化症、脑肿瘤或丁酰胆碱酯酶活性的诊断。 | |||
T78426 |
MCAAD-3
|
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MCAAD-3为一种近红外Aβ成像探针,能穿透血脑屏障。其对Aβ聚合体拥有高亲和力(Ki >106 nM),能够在转基因小鼠大脑中标记Aβ斑块。 | |||
T78076 |
PBR28
|
Others | Others |
PBR28是一种TSPO调节剂,适用于肺动脉高压(PAH)预防研究。通过增加放射性标记的PBR28能够示踪18KDa转运蛋白(TSPO),在脑正电子发射断层扫描(PET)成像中具有关键作用。 | |||
T8406L |
Gadobutrol Monohydrate
Gd-DO3A-butrol |
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Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by high | |||
T61087 |
THK-5105
|
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THK-5105为芳基喹啉衍生物,具备与tau原纤维高度结合的亲和力。它对tau蛋白聚集体及含tau的阿尔茨海默病(AD)脑匀浆显示出显著的结合能力。18F-THK-5105展现出作为tau成像PET探针的潜能。 | |||
T60907 | THK-5117 | ||
THK-5117 是一种芳基喹啉衍生物,具有作为 tau 成像 PET 探针的潜力。THK-5117 对 tau 原纤维表现出高结合亲和力,Ki 值为 10.5 nM。THK-5117 还显示出对 tau 蛋白聚集体和富含 tau 的阿尔茨海默病 (AD) 脑匀浆的高结合亲和力。 | |||
T36499 |
CuATSM
|
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The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic lateral sclerosis (ALS). Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that has traditionally been used in cellular imaging experiments to selectively label hypoxic tissue via its susceptibility ... |