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Search Results for " b-galactosidase "

4

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T37439	C18 Globotriaosylceramide (d18:1/18:0)
	C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosoma...
T35806	N-Stearoylsphingosine C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide	Phosphatase	Metabolism
	N-Stearoylsphingosine (Cer(d18:1/18:0)) 是一种广泛存在真核生物体内的酰胺类化合物，通过干扰PP2A与PP2A抑制剂2的结合来增强蛋白质磷酸酶2A(PP2A)活性，导致Akt去磷酸化。N-Stearoylsphingosine 可用于研究前列腺癌。
T37457	C18 L-threo Ceramide (d18:1/18:0) C18 L-threo Ceramide (d18:1/18:0)
	C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.21 mol% (16.8 μM).
T37456	C18 L-erythro Ceramide (d18:1/18:0) C18 L-erythro Ceramide (d18:1/18:0)
	C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide . It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.11 mol% (8.8 μM).

化合物

C18 Globotriaosylceramide (d18:1/18:0)

Cat.No: T37439

N-Stearoylsphingosine

Cat.No: T35806

Synonym: C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide

Target: Phosphatase

C18 L-threo Ceramide (d18:1/18:0)

Cat.No: T37457

Synonym: C18 L-threo Ceramide (d18:1/18:0)

C18 L-erythro Ceramide (d18:1/18:0)

Cat.No: T37456

Synonym: C18 L-erythro Ceramide (d18:1/18:0)

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00869	GLB1 Protein, Human, Recombinant (His) Lactase,Acid Beta-Galactosidase,Elastin Re...	Human	HEK293 Cells
	β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-ga...
TMPJ-00728	Beta-galactosidase Protein, E. coli, Recombinant Beta-gal,Beta-galactosidase,lacZ,...	E. coli	E. coli
	β-galactosidase is an exoglycosidase which hydrolyzes the β-glycosidic bond formed between a galactose and its organic moiety. It may also cleave fucosides and arabinosides but with much lower efficiency. β-galactosides include carbohydrates containing galactose where the glycosidic bond lies above the galactose molecule. Substrates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins. It is an essential enzyme in the human body. Deficienci...
TMPH-00129	Probable Alpha Galactosidase B Protein, Aspergillus niger, Recombinant (His)	Aspergillus niger	P. pastoris (Yeast)
	Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides. Probable Alpha Galactosidase B Protein, Aspergillus niger, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 48.7 kDa and the accession number is A2QEJ9.
TMPH-03125	Saposin-B-Val Protein, Pig, Recombinant (Flag & His)	Sus scrofa (Pig)	P. pastoris (Yeast)
	Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-B-Val Protein, Pig, Recombinant (Flag & His) is expressed in yeast with N-6xHis-Flag tag. The predicted molecular weight is 11.9 kDa and the accession number is P81405.
TMPK-01413	H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) H-2K,OVA,MHC,H2-K1	Mouse	HEK293 Cells
	Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01416	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,SARS-CoV-2 epitope	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01412	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) SARS-CoV-2 epitope,MHC	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

GLB1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00869

Species: Human

Expression System: HEK293 Cells

Beta-galactosidase Protein, E. coli, Recombinant

Cat.No: TMPJ-00728

Species: E. coli

Expression System: E. coli

Probable Alpha Galactosidase B Protein, Aspergillus niger, Recombinant (His)

Cat.No: TMPH-00129

Species: Aspergillus niger

Expression System: P. pastoris (Yeast)

Saposin-B-Val Protein, Pig, Recombinant (Flag & His)

Cat.No: TMPH-03125

Species: Sus scrofa (Pig)

Expression System: P. pastoris (Yeast)

H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

Cat.No: TMPK-01413

Species: Mouse

Expression System: HEK293 Cells

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01416

Species: Human

Expression System: HEK293 Cells

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01412

Species: Human

Expression System: HEK293 Cells

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