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Search Results for " asd "

Targets Recommended: Hedgehog/Smoothened Smo

4

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6514	Glasdegib PF-04449913	Hedgehog/Smoothened; Smo	GPCR/G Protein; Stem Cells
	Glasdegib (PF-04449913) 是一种口服具有活力的 smoothened 抑制剂，能够结合到人 SMO(181-787氨基酸位点)，IC50=4 nM。
T80568	Casdozokitug SRF-388
	Casdozokitug (SRF-388) 是一种针对IL27的IgG1κ类型抗体。
T71455	Glasdegib hydrochloride
	Glasdegib hydrochloride is a small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity.
T27966	M1000907 M-1000907,M 1000907
	M1000907 is a selective 5-HT2A receptor antagonist. It may interfere with altered 5-HT2A receptor signaling that contributes to ASD symptoms.

化合物

Cat.No: T6514

Synonym: PF-04449913

Target: Hedgehog/Smoothened, Smo

Cat.No: T80568

Synonym: SRF-388

Glasdegib hydrochloride

Cat.No: T71455

Cat.No: T27966

Synonym: M-1000907,M 1000907

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02398	ASA dehydrogenase Protein, Legionella pneumophila, Recombinant (His) Aspartate-beta-semialdehyde dehydrogenase,asd,Aspar...	Legionella pneumophila	E. coli
	Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
TMPH-01375	Gasdermin-C Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	Gasdermin-C Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 61.7 kDa and the accession number is Q9BYG8.
TMPH-02670	Gasdermin-A3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Precursor of a pore-forming protein involved in the transition from catagen to telogen at the end of hair follicle morphogenesis. This form constitutes the precursor of the pore: upon cleavage, the released N-terminal moiety (Gasdermin-A3, N-terminal) binds to membranes and forms pores, triggering cell death.; Pore-forming protein that causes membrane permeabilization and pyroptosis. Released upon cleavage in vitro of genetically engineered Gsdma3, and binds to membrane inner leaflet lipids. Hom...
TMPH-01374	Gasdermin-B Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Gasdermin-B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.2 kDa and the accession number is Q8TAX9.
TMPH-01376	Gasdermin-C Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Gasdermin-C Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.7 kDa and the accession number is Q9BYG8.
TMPH-02671	Gasdermin-D Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis.; Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4/CASP11 in response to canon...
TMPY-01118	SLC27A4/FATP4 Protein, Human, Recombinant (His) FATP4,IPS,solute carrier family 27 (fatty acid transporter),...	Human	HEK293 Cells
	SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism spectrum disorders (ASD) are now recognized as disorders caused by impaired early brain development, it is possible that functional abnormalities of SLC27A genes may contribute to the pathogenesis of ASD. The expression of SLC27A3 and SLC27A4 in human neural stem cells derived fro...

重组蛋白

ASA dehydrogenase Protein, Legionella pneumophila, Recombinant (His)

Cat.No: TMPH-02398

Species: Legionella pneumophila

Expression System: E. coli

Gasdermin-C Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01375

Species: Human

Expression System: Baculovirus Insect Cells

Gasdermin-A3 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02670

Species: Mouse

Expression System: E. coli

Gasdermin-B Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01374

Species: Human

Expression System: E. coli

Gasdermin-C Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01376

Species: Human

Expression System: E. coli

Gasdermin-D Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02671

Species: Mouse

Expression System: E. coli

SLC27A4/FATP4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01118

Species: Human

Expression System: HEK293 Cells

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