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163

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T3189	B7/CD28 interaction inhibitor 1 CTLA-4 inhibitor	Others	Others
	B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) 是B7.1-CD28相互作用抑制剂(IC50:50 nM)。
T18896	5(6)-FITC Fluorescein 5(6)-isothiocyanate,异硫氰酸荧光素,Fluorescein isothiocyanate	Others	Others
	5(6)-FITC (Fluorescein isothiocyanate), or Fluorescein 5(6)-isothiocyanate, is a versatile amine-reactive derivative of fluorescein dye. It serves as an effective label for antibodies and other probes, finding utility in fluorescence microscopy, flow cytometry, and immunofluorescence-based assays such as ELISA and Western blotting.
T18956	CY7 Sulfo-Cyanine7	Others	Others
	CY7 (Sulfo-Cyanine7) 是一种荧光标记试剂 (Ex=750 nm，Em=773 nm)。Cyanine 染料可用于标记抗体，蛋白质，肽，寡聚核苷酸等。
T18954L	CY7-SE Triethylamine (477908-53-5(free acid) )	Others	Others
	CY7-SE Triethylamine (477908-53-5(free acid) ) 是一种荧光标记剂（Ex=700-770 nm，Em=790 nm），用于标记蛋白质、肽、抗体和寡核苷酸。
T14578	Biotin Hydrazide	Others	Others
	Biotin Hydrazide 是一种羰基反应性生物素化试剂，是羰基探针。
T18946	Cy3 NHS ester Cyanine3 NHS ester	Others	Others
	Cy3 NHS ester (Cyanine3 NHS ester) 是一种荧光染料，用于标记蛋白质、肽、抗体和寡核苷酸中的氨基。
T29087	VA-K-14 hydrochloride VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl	TSH Receptor	GPCR/G Protein
	VA-K-14 hydrochloride（VAK14 HCl）是一种选择性促甲状腺激素受体 (TSHR) 拮抗剂 (IC50= 12.3 μM)，对GD患者血清和单克隆刺激TSHR抗体对TSHR的刺激有抑制作用，可消除 TSHR 信号传导。
T4346	SPDB	Others	Others
	SPDB 是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。它是一个与 DM4 偶联物相连的小片段，利用二硫键与抗体偶联。
T18905	6-TAMRA 6-羧基四甲基罗丹明,6-Carboxytetramethylrhodamine	Others	Others
	6-TAMRA (6-Carboxytetramethylrhodamine) 常用作制备生物偶联物的荧光团，尤其是用于免疫化学的荧光抗体剂抗生物素蛋白衍生物。
T18983	DNP-X acid 6-((2,4-Dinitrophenyl)amino)hexanoic acid	Others	Others
	DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid) 是一种与 Trp 或 Tyr 配对的极好的胺反应性 FRET 淬灭剂，能够用于开发可被 anti-DNP 抗体识别的探针的胺反应性构建块。
T17946	Fmoc-Ala-Ala-Asn(Trt)-OH	Others	Others
	Fmoc-Ala-Ala-Asn(Trt)-OH 是一种可切割的 ADC 接头，用于抗体-药物偶联物。
T8670	fmoc-L-2-cyanophenylalanine	Others	Others
	fmoc-L-2-cyanophenylalanine 是氨基酸苯丙氨酸的衍生物，由于其优异的反应性和稳定性，被广泛用于肽合成，以及合成各种其他生物活性分子，如肽激素、酶和抗体。
TP1865L	Rhodopsin Epitope Tag acetate	Others	Others
	Rhodopsin Epitope Tag acetate 是一种 9 个氨基酸的肽，代表牛视紫红质的 C 末端，广泛用作表位标签。许多抗视紫红质抗体可以识别该表位。
TP1805	T7 Tag Peptide
	T7 Tag Peptide 是一个由T7噬菌体编码的蛋白p10前导序列的11个氨基酸标记蛋白，可以被T7 tag标签抗体特异性识别，可用于不同的免疫检测以及亲和纯化。
T38681	P-SCN-Bn-DOTA	Others	Others
	p-SCN-Bn-DOTA 是一种螯合剂，可同时螯合放射性核素和连接单克隆抗体，可作为放射引导手术的示踪剂，可用于肿瘤的放射免疫研究。
T18321	Mc-Val-Cit-PAB-Cl	Others	Others
	Mc-Val-Cit-PAB-Cl 是一种可切割的 ADC 接头，可用于偶联 MMAE 和抗体以形成抗体-MC-vc-MMAE。
T18984	DNP-X, SE 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester	Others	Others
	DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) 是一种用于开发可被 anti-DNP 抗体识别的探针的胺反应性构建块，是经过琥珀酰亚胺酯修饰的 DNP-X acid。它也是一种能够与 Trp 或 Tyr 配对的极好的胺反应性 FRET 淬灭剂。
T76742	Emapalumab NI-0501	COX	Immunology/Inflammation; Neuroscience
	Emapalumab (NI-0501) 是一种人源化针对干扰素 γ 的人单克隆抗体的 IgG1 单克隆抗体，可阻断其与细胞表面受体的结合并激活炎症信号。Emapalumab 与游离的 IFN-γ 以及与其受体结合的 IFN-γ 具有高结合力 (Kd=1.4 pM)。Emapalumab 可用于噬血细胞性淋巴组织细胞增多症 (HLH) 的研究。
T71850	2',3'-Isopropylideneuridine
	2',3'-Isopropylideneuridine has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies.
T40927	DOTA-tris(tBu)ester NHS ester
	DOTA-tris(tBu)ester NHS ester, a derivative of DOTA, serves for the labeling of peptides and antibodies.
T25727	LiLo
	LiLo is used as a chelating agent for attaching indium-111 to monoclonal antibodies.
T41026	Biotin-LC-LC-NHS
	Biotin-LC-LC-NHS is a SMCC cross-linking reagent, which serves as a labeling agent for antibodies and small molecules, like Paclitaxel.
T38997	BCN-PEG4-HyNic BCN-PEG4-HyNic
	BCN-PEG4-HyNic is a cleavable four-unit PEG linker utilized in ADC synthesis for coupling drugs to antibodies, creating antibody-drug conjugates (ADCs).
T17379	Ald-Ph-amido-PEG1-C2-NHS ester	Others	Others
	Ald-Ph-amido-PEG1-C2-NHS ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
TD0028	Super Fluor 680, SE
	This Super Fluor 680, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection.
T17381	Ald-Ph-amido-PEG2-C2-Pfp ester	Others	Others
	Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
T18564	Propargyl-O-C1-amido-PEG4-C2-NHS ester	Others	Others
	Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
T38971	Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2
	Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable linker employed in ADC synthesis for conjugation with antibodies, ultimately producing antibody-drug conjugates (ADCs).
T12706	Reslizumab Sch 55700	IL Receptor	Immunology/Inflammation
	Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma.
T41000	N-trifluoroacetyl-β-alanyl chloride
	N-trifluoroacetyl-β-alanyl chloride is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs), which are bioconjugates formed by attaching drug molecules to antibodies.
T17811	DBCO-SS-aldehyde	Others	Others
	DBCO-SS-aldehyde is an ADC linker employed for ADC synthesis[1]. This cleavable linker is designed to facilitate the conjugation of antibodies and drugs, resulting in antibody-drug conjugates (ADCs).
T18955	Cy7-YNE	Others	Others
	Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm,Em=790 nm) used for labeling antibodies, proteins, and peptides.
T14724	Boc-Cystamine	Others	Others
	Boc-Cystamine is a cleavable linker vital in ADC synthesis. Boc-Cystamine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T17151	Tr-PEG4-OH	Others	Others
	Tr-PEG4-OH is a non-cleavable tetraethylene glycol ADC linker employed in ADC synthesis for the conjugation of antibodies and drugs.
T39880	Propargyl-Tos
	Propargyl-Tos is a cleavable linker vital in ADC synthesis. Propargyl-Tos joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T17835	DMAC-PDB	Others	Others
	DMAC-PDB is a cleavable linker vital in ADC synthesis. DMAC-PDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T78336	Mouse IgG1 kappa, Isotype Control
	MouseIgG1kappa Isotype Control 为 mouse IgG1κ 抗体的同型对照鼠源单克隆抗体。
T16628	Propargyl-PEG4-NHS ester	Others	Others
	Propargyl-PEG4-NHS ester is a non-cleavable 4-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
T14627	Bis-PEG1-NHS ester	Others	Others
	Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
T40762	NO2-SPDB-sulfo NO2-SPDB-sulfo
	NO2-SPDB-sulfo is a cleavable linker vital in ADC synthesis. NO2-SPDB-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T18786	TCO-SS-amine	Others	Others
	TCO-SS-amine is a cleavable linker vital in ADC synthesis. TCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T17812	DBCO-SS-amine	Others	Others
	DBCO-SS-amine is a cleavable linker vital in ADC synthesis. DBCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T81756	Mouse IgG3 kappa, Isotype Control
	MouseIgG3kappa, Isotype Control为鼠源单克隆抗体，充当mouse IgG3κ抗体的同型对照。
T35421	2'-O-Succinyl-cAMP
	2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2
T39023	Biotin-sar-oh
	Biotin-sar-oh is a cleavable linker vital in ADC synthesis. Biotin-sar-oh joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T40763	NO2-SPDMV-sulfo NO2-SPDMV-sulfo
	NO2-SPDMV-sulfo is a cleavable linker vital in ADC synthesis. NO2-SPDMV-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T17387	Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP	Others	Others
	Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs), which are innovative therapeutic agents that combine the targeting ability of antibodies with potent cytotoxic drugs.
T39087	MC-VC-PAB-NH2 MC-VC-PAB-NH2
	MC-VC-PAB-NH2 is a cleavable linker vital in ADC synthesis. MC-VC-PAB-NH2 joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
TD0030	Super Fluor 750, SE
	This Super Fluor 750, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection.
T16587	Propargyl-PEG1-NHS ester	Others	Others
	Propargyl-PEG1-NHS ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

化合物

B7/CD28 interaction inhibitor 1

Cat.No: T3189

Synonym: CTLA-4 inhibitor

Target: Others

Cat.No: T18896

Synonym: Fluorescein 5(6)-isothiocyanate,异硫氰酸荧光素,Fluorescein isothiocyanate

Target: Others

Cat.No: T18956

Synonym: Sulfo-Cyanine7

Target: Others

CY7-SE Triethylamine (477908-53-5(free acid) )

Cat.No: T18954L

Target: Others

Biotin Hydrazide

Cat.No: T14578

Target: Others

Cat.No: T18946

Synonym: Cyanine3 NHS ester

Target: Others

VA-K-14 hydrochloride

Cat.No: T29087

Synonym: VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl

Target: TSH Receptor

Cat.No: T4346

Target: Others

Cat.No: T18905

Synonym: 6-羧基四甲基罗丹明,6-Carboxytetramethylrhodamine

Target: Others

Cat.No: T18983

Synonym: 6-((2,4-Dinitrophenyl)amino)hexanoic acid

Target: Others

Fmoc-Ala-Ala-Asn(Trt)-OH

Cat.No: T17946

Target: Others

fmoc-L-2-cyanophenylalanine

Cat.No: T8670

Target: Others

Rhodopsin Epitope Tag acetate

Cat.No: TP1865L

Target: Others

Cat.No: TP1805

Cat.No: T38681

Target: Others

Mc-Val-Cit-PAB-Cl

Cat.No: T18321

Target: Others

Cat.No: T18984

Synonym: 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester

Target: Others

Cat.No: T76742

Synonym: NI-0501

Target: COX

2',3'-Isopropylideneuridine

Cat.No: T71850

DOTA-tris(tBu)ester NHS ester

Cat.No: T40927

Cat.No: T25727

Biotin-LC-LC-NHS

Cat.No: T41026

Cat.No: T38997

Synonym: BCN-PEG4-HyNic

Ald-Ph-amido-PEG1-C2-NHS ester

Cat.No: T17379

Target: Others

Super Fluor 680, SE

Cat.No: TD0028

Ald-Ph-amido-PEG2-C2-Pfp ester

Cat.No: T17381

Target: Others

Propargyl-O-C1-amido-PEG4-C2-NHS ester

Cat.No: T18564

Target: Others

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2

Cat.No: T38971

Synonym: Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2

Cat.No: T12706

Synonym: Sch 55700

Target: IL Receptor

N-trifluoroacetyl-β-alanyl chloride

Cat.No: T41000

DBCO-SS-aldehyde

Cat.No: T17811

Target: Others

Cat.No: T18955

Target: Others

Cat.No: T14724

Target: Others

Cat.No: T17151

Target: Others

Cat.No: T39880

Cat.No: T17835

Target: Others

Mouse IgG1 kappa, Isotype Control

Cat.No: T78336

Propargyl-PEG4-NHS ester

Cat.No: T16628

Target: Others

Bis-PEG1-NHS ester

Cat.No: T14627

Target: Others

Cat.No: T40762

Synonym: NO2-SPDB-sulfo

Cat.No: T18786

Target: Others

Cat.No: T17812

Target: Others

Mouse IgG3 kappa, Isotype Control

Cat.No: T81756

2'-O-Succinyl-cAMP

Cat.No: T35421

Cat.No: T39023

NO2-SPDMV-sulfo

Cat.No: T40763

Synonym: NO2-SPDMV-sulfo

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP

Cat.No: T17387

Target: Others

Cat.No: T39087

Synonym: MC-VC-PAB-NH2

Super Fluor 750, SE

Cat.No: TD0030

Propargyl-PEG1-NHS ester

Cat.No: T16587

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2145	Retronecine	Others	Others
	Retronecine acts as the better competitor for the competitive inhibition of antibodies to Retronecine.
T72858	Maydispenoid B
	Maydispenoid B，一种有效的免疫抑制剂，能够抑制抗CD3/抗CD28单抗和脂多糖激活的小鼠脾细胞增殖。
T72857	Maydispenoid A
	Maydispenoid A, 作为一种有效的免疫抑制剂，能够抑制抗CD3/抗CD28单抗和脂多糖激活的小鼠脾细胞增殖。

天然产物

Cat.No: TN2145

Target: Others

Cat.No: T72858

Cat.No: T72857

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