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10

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T39792 AMPC

AMPC, a powerful and efficient inhibitor of TFF3, demonstrates inhibitory effects on cell proliferation, survival, oncogenicity, and CSC-like behavior in TFF3-positive CMS4 CRC cells. It acts as a promising standalone anti-cancer agent and also enhances the effects of 5-FU when used in combination, making it a valuable tool for cancer research.
T71538 AMPCP

AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.
T5570 Cephalothin

头孢噻吩,Cephalotin acid

Antibacterial; Antibiotic Microbiology/Virology
Cephalothin 是一种 β-内酰胺抗生素,抑制 C 类 β-内酰胺酶活性的 Ki 值为 0.32 µM。
T11125 Durlobactam sodium salt

杜巴坦,ETX2514 sodium salt,杜洛巴坦

Antibacterial Microbiology/Virology
Durlobactam sodium salt (ETX2514 sodium salt)是一种 β-内酰胺酶抑制剂,针对 A 类 KPC-2、C 类 AmpC 和 D 类 OXA-24,IC50 值分别为 4 nM、14 nM 和 190 nM。 Durlobactam sodium salt 可用于对包括鲍曼不动杆菌在内的耐药革兰氏阴性菌的研究。
T60050 ANT3310

Antibacterial Microbiology/Virology
ANT3310 是一种广谱共价丝氨酸 β-内酰胺酶抑制剂,对 AmpC、CTX-M-15、TEM-1、OXA-48、OXA-23 和 KPC-2 的 IC50 范围为 1 nM 至 175 nM。 ANT3310 可用于细菌感染研究。
T13077 Taniborbactam dihydrochloride

VNRX-5133 dihydrochloride,Taniborbactam 2HCl

Antibacterial; Antifungal Microbiology/Virology
Taniborbactam dihydrochloride (VNRX-5133 dihydrochloride) 是一种具有选择性和有效性的新型环硼酸β-内酰胺酶抑制剂,具有抗菌活性,对革兰氏阴性菌抑制作用显著。Taniborbactam dihydrochloride 抑制 KPC-2,AmpC,OXA-48 和 VIM-2 ,可以用于研究真菌感染。
T13077L Taniborbactam

VNRX-5133

Antibacterial Microbiology/Virology
Taniborbactam is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor (IC50s: 8-530 nM). Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2.
T39758 ARX-1796

ARX-1796,AV-006

ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes.
T38458 Faropenem

Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory...
T71669 BLI-489 Hydrate

BLI-489 hydrate 是一种青霉烯类 β-内酰胺酶抑制剂,能够作用于 A 类和 C 类以及一些 D 类 β-内酰胺酶。Piperacillin 与 BLI-489 hydrate 联用,能够有效治疗 A 类 (包括超广谱 β-内酰胺酶)、C 类 (AmpC) 和 D 类 β-内酰胺酶表达病原体引起的小鼠感染。

化合物

AMPC
Cat.No: T39792
Synonym:
Target:
AMPCP
Cat.No: T71538
Synonym:
Target:
Cephalothin
Cat.No: T5570
Synonym: 头孢噻吩,Cephalotin acid
Target: Antibacterial, Antibiotic
Durlobactam sodium salt
Cat.No: T11125
Synonym: 杜巴坦,ETX2514 sodium salt,杜洛巴坦
Target: Antibacterial
ANT3310
Cat.No: T60050
Synonym:
Target: Antibacterial
Taniborbactam dihydrochloride
Cat.No: T13077
Synonym: VNRX-5133 dihydrochloride,Taniborbactam 2HCl
Target: Antibacterial, Antifungal
Taniborbactam
Cat.No: T13077L
Synonym: VNRX-5133
Target: Antibacterial
ARX-1796
Cat.No: T39758
Synonym: ARX-1796,AV-006
Target:
Faropenem
Cat.No: T38458
Synonym:
Target:
BLI-489 Hydrate
Cat.No: T71669
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-00588 Beta-lactamase Protein, E. coli, Recombinant (His & SUMO)

ampC,Cephalosporinase,ampA,Beta-lactamase

E. coli E. coli
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
TMPH-03165 Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Beta-lactamase,ampC,ampA,Cephalosporinase

Pseudomonas aeruginosa E. coli
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735.

重组蛋白

Beta-lactamase Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00588
Species: E. coli
Expression System: E. coli
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Cat.No: TMPH-03165
Species: Pseudomonas aeruginosa
Expression System: E. coli
TargetMol Loading
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