10
2
Cat. No. | Product Name | Target | Signaling Pathways |
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T39792 |
AMPC
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AMPC, a powerful and efficient inhibitor of TFF3, demonstrates inhibitory effects on cell proliferation, survival, oncogenicity, and CSC-like behavior in TFF3-positive CMS4 CRC cells. It acts as a promising standalone anti-cancer agent and also enhances the effects of 5-FU when used in combination, making it a valuable tool for cancer research. | |||
T71538 |
AMPCP
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AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor. | |||
T5570 |
Cephalothin
头孢噻吩,Cephalotin acid |
Antibacterial; Antibiotic | Microbiology/Virology |
Cephalothin 是一种 β-内酰胺抗生素,抑制 C 类 β-内酰胺酶活性的 Ki 值为 0.32 µM。 | |||
T11125 |
Durlobactam sodium salt
杜巴坦,ETX2514 sodium salt,杜洛巴坦 |
Antibacterial | Microbiology/Virology |
Durlobactam sodium salt (ETX2514 sodium salt)是一种 β-内酰胺酶抑制剂,针对 A 类 KPC-2、C 类 AmpC 和 D 类 OXA-24,IC50 值分别为 4 nM、14 nM 和 190 nM。 Durlobactam sodium salt 可用于对包括鲍曼不动杆菌在内的耐药革兰氏阴性菌的研究。 | |||
T60050 |
ANT3310
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Antibacterial | Microbiology/Virology |
ANT3310 是一种广谱共价丝氨酸 β-内酰胺酶抑制剂,对 AmpC、CTX-M-15、TEM-1、OXA-48、OXA-23 和 KPC-2 的 IC50 范围为 1 nM 至 175 nM。 ANT3310 可用于细菌感染研究。 | |||
T13077 |
Taniborbactam dihydrochloride
VNRX-5133 dihydrochloride,Taniborbactam 2HCl |
Antibacterial; Antifungal | Microbiology/Virology |
Taniborbactam dihydrochloride (VNRX-5133 dihydrochloride) 是一种具有选择性和有效性的新型环硼酸β-内酰胺酶抑制剂,具有抗菌活性,对革兰氏阴性菌抑制作用显著。Taniborbactam dihydrochloride 抑制 KPC-2,AmpC,OXA-48 和 VIM-2 ,可以用于研究真菌感染。 | |||
T13077L |
Taniborbactam
VNRX-5133 |
Antibacterial | Microbiology/Virology |
Taniborbactam is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor (IC50s: 8-530 nM). Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. | |||
T39758 |
ARX-1796
ARX-1796,AV-006 |
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ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes. | |||
T38458 |
Faropenem
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Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory... | |||
T71669 |
BLI-489 Hydrate
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BLI-489 hydrate 是一种青霉烯类 β-内酰胺酶抑制剂,能够作用于 A 类和 C 类以及一些 D 类 β-内酰胺酶。Piperacillin 与 BLI-489 hydrate 联用,能够有效治疗 A 类 (包括超广谱 β-内酰胺酶)、C 类 (AmpC) 和 D 类 β-内酰胺酶表达病原体引起的小鼠感染。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-00588 |
Beta-lactamase Protein, E. coli, Recombinant (His & SUMO)
ampC,Cephalosporinase,ampA,Beta-lactamase |
E. coli | E. coli |
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | |||
TMPH-03165 |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Beta-lactamase,ampC,ampA,Cephalosporinase |
Pseudomonas aeruginosa | E. coli |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735. |