Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3990 |
AA26-9
|
Phospholipase; Serine Protease | Metabolism; Proteases/Proteasome |
AA26-9 是广谱丝氨酸水解酶的高效抑制剂。它的靶点包括丝氨酸肽酶、酰胺酶、脂肪酶、酯酶和硫酯酶。在永生化 T 细胞系,检测到它对 40+ 丝氨酸水解酶中的 1/3 有抑制作用。 | |||
T80051 |
Amidase
|
Endogenous Metabolite | Metabolism |
Amidases属于腈水解酶超家族,专门催化酰胺水解成羧酸和氨。该酶含有一个约130个氨基酸组成的保守序列,即AS序列,在关键代谢过程中扮演重要角色。 | |||
T37996 |
17-phenyl trinor Prostaglandin E2 ethyl amide
17-phenyl trinor Prostaglandin E2 ethyl amide |
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17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively). 17-phenyl trinor PGE2 causes contraction of guinea pig ileum at a concentration of 11 μM and is 4.4 times more potent than PGE2 as an antifertility agent in hamsters. Modification of the C-1 carboxyl group to an ethyl amide serves to inc... |