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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7941 |
Imipramine hydrochloride
盐酸丙咪嗪,Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine |
Serotonin Transporter | Neuroscience |
Imipramine hydrochloride (Imipramine HCl) 可抑制血清素转运蛋白,IC50=32 nM。它可阻止胰酶的易位,阻碍 MV 和外泌体的分泌。 | |||
T11835L |
LCL521 dihydrochloride
1,3DMG-B13 dihydrochloride |
Others | Others |
LCL521 dihydrochloride is a compound that functions as an inhibitor of both acid ceramidase (ACDase) and lysosomal acid sphingomyelinase (ASMase). | |||
T11835 |
LCL521
|
Others; Phospholipase | Metabolism; Others |
LCL521 能抑制溶酶体酸性鞘磷脂酶(ASMase)。LCL521 是一种酸性神经酰胺酶(ACDase)抑制剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02585 |
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
aSMase,ASM,Zn-SMase,A-SMase,sphingomyelin phosphodi... |
Mouse | Baculovirus Insect Cells |
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monome... |