Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13387L |
Zatebradine hydrochloride
UL-FS-49CL,UL-FS-49 |
Others; HCN Channel | Membrane transporter/Ion channel; Others |
Zatebradine hydrochloride (UL-FS-49CL) 是一种高效的 、有效的HCN Channel 抑制剂( IC50 :1.96 µM)。 HCN Channel 是一种有效的超极化激活环核苷酸门控通道。 Zatebradine hydrochloride 阻止通过人类 HCN1,HCN2,HCN3 和 HCN4 通道的缓慢内向电流,其 IC50 值分别为 1.83 µM,2.21 µM,1.90 µM 和 1.88 µM。 | |||
T13387 |
Zatebradine
UL-FS-49 free base,UL-FS-49CL free base |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Zatebradine is a potent hyperpolarization-activated cyclic nucleotide-gated (HCN) channels inhibitor(IC50 of 1.96 µM). |