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Cat. No. Product Name Target Signaling Pathways
T5468 YF-2

Others; Epigenetic Reader Domain; Histone Acetyltransferase Chromatin/Epigenetic; Others
YF-2 是一种高选择性,可透过血脑屏障的组蛋白乙酰转移酶激动剂,能够在海马区乙酰化 H3,对 CBP、PCAF 和 GCN5 的EC50值分别为 2.75、29.04 和 49.31 μM,具有抗肿瘤和抗阿尔滋海默症的活性。
T38711 YF-2 hydrochloride

YF-2 hydrochloride is a potent histone acetyltransferase activator that exhibits high selectivity and can pass through the blood-brain barrier. It specifically acetylates H3 in the hippocampus, with EC50 values of 2.75 μM, 29.04 μM, and 49.31 μM for CBP, PCAF, and GCN5, respectively. Notably, it does not affect HDAC activity. Moreover, YF-2 hydrochloride demonstrates promising anti-cancer and anti-Alzheimer's disease properties.

化合物

YF-2
Cat.No: T5468
Synonym:
Target: Others, Epigenetic Reader Domain, Histone Acetyltransferase
YF-2 hydrochloride
Cat.No: T38711
Synonym:
Target:
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