Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13317 |
VU0364770 hydrochloride
|
Others | Others |
VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively). | |||
T6727 |
VU0364770
VU 0364770 |
GluR | Neuroscience |
VU0364770 (VU 0364770) 是一种选择性mGlu4正变构调节剂,对 mGlu5 具有拮抗活性,对 mGlu6 具有正变构调节活性。它还对 MAO 具有活性,对人 MAO-A 和 MAO-B 的 Ki 值分别为8.5 和 0.72 μM。 |