Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17922 |
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
VHL Ligand-Linker Conjugates 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 5,VH032-PEG3-NH2 hydrochloride,VHL Ligand-Linker Conjugates 1 HCl |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) 是一种 E3 ligase ligand-linker conjugate,包含了 (S,R,S)-AHPC-based VHL ligand 和 3-unit PEG linker。 | |||
T17920 |
(S,R,S)-AHPC-PEG1-N3
VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) 是 E3 连接酶配体和linker 连接得到的 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个单元 PEG linker。 | |||
T17905 |
(S,R,S)-AHPC-PEG1-OTs
VH032-PEG1-OTs,VHL Ligand-Linker Conjugates 2,E3 ligase Ligand-Linker Conjugates 51 |
Others | Others |
(S,R,S)-AHPC-PEG1-OTs is a chemically synthesized conjugate, functioning as an ligase ligand-linker for E3 ligase. It incorporates the VHL ligand derived from (S,R,S)-AHPC and a 1-unit PEG linker. This synthesized compound is commonly employed in PROTAC technology. | |||
T17923 |
(S,R,S)-AHPC-PEG3-NH2
E3 ligase Ligand-Linker Conjugates 5 Free Base,VH032-PEG3-NH2,VHL Ligand-Linker Conjugates 1 |
Others | Others |
(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology. | |||
T17908 |
VHL Ligand-Linker Conjugates 15
E3 Ligase Ligand-Linker Conjugates 56 |
Others | Others |
VHL Ligand-Linker Conjugates 15 is a chemical compound that combines a VHL ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is specifically designed for the creation of PROTACs[1]. | |||
T18873 |
VHL Ligand-Linker Conjugates 17
|
Others | Others |
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, including the notable ARD-266. ARD-266 is an exceptionally effective androgen receptor (AR) PROTAC degrader[1]. |