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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0698	Dioxybenzone UV-24,二羟苯宗,Benzophenone-8,2,2'-Dihydroxy-4-methoxybenzophenone,Dioxybenzon,Cyasorb UV 24,Advastab 47	Others	Others
	Dioxybenzone (Benzophenone-8) 是一种能够阻断 UVB 和短波 UVA 紫外线照射的有机试剂。
T16914	SP187 UV4,MON-DNJ	Others; Virus Protease; Influenza Virus	Microbiology/Virology; Others
	SP187 (MON-DNJ) 是一种靶向作用于宿主的亚氨基糖。它具有抗丝状病毒感染活性。SP187可用于治疗抗流感和登革热病毒。
T70952	UR-MK299
	UR-MK299 is a NPY Y1 receptor antagonist.
T7465	4-Methylbenzylidene camphor Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC	AChE	Neuroscience
	4-Methylbenzylidene camphor 是有机的樟脑衍生物，应用于化妆品行业，具有保护皮肤抵抗紫外线（特别是紫外线B 辐射）的能力。
T36894	5-Bromouridine
	5-Bromouridine is a brominated analog of the nucleoside uridine .1It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine .25-Bromouridine decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively). It induces apoptosis and halts the cell cycle at the S phase in HL-60 cells. It is photoreactive, and UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of of RNA-protein interactions....
T35817	Photoswitchable PAD Inhibitor (technical grade)
	Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without photoactivation, it is a weak inhibitor of PAD2 (IC50 = >100 μM) and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro (kinact/KIs = 2,300, 600, 1,000, and 10,510 M-1min-1 for PAD1-4, respectively) and does not inhibit histone H3 citrullination in HEK29...
T36400	para-amino-Blebbistatin
	para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases that rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM).2,3,4 Through these effects, it blocks ap...

化合物

Dioxybenzone

Cat.No: T0698

Synonym: UV-24,二羟苯宗,Benzophenone-8,2,2'-Dihydroxy-4-methoxybenzophenone,Dioxybenzon,Cyasorb UV 24,Advastab 47

Target: Others

SP187

Cat.No: T16914

Synonym: UV4,MON-DNJ

Target: Others, Virus Protease, Influenza Virus

4-Methylbenzylidene camphor

Cat.No: T7465

Synonym: Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC

Photoswitchable PAD Inhibitor (technical grade)

Cat.No: T35817

Synonym:

Target:

para-amino-Blebbistatin

Cat.No: T36400

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T4759	Urocanic acid 4-Imidazoleacrylic acid,尿刊酸	Others; Endogenous Metabolite	Metabolism; Others
	Urocanic acid（4-Imidazoleacrylic acid）存在于表皮中，是哺乳动物皮肤中紫外线（UV）辐射的主要吸收物。
T1311	4-aminobenzoic acid PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸	Endogenous Metabolite	Metabolism
	4-aminobenzoic acid (para-Aminobenzoic acid) 是一种具有紫外线吸收和抗纤维化特性的有机酸。当暴露在光线下时，4-aminobenzoic acid 吸收紫外线并通过光化学反应释放多余的能量，这可能会对DNA造成损害。4-aminobenzoic acid 还可以增加组织水平的摄氧量，并可能增强单胺氧化酶(MAO)活性以促进血清素的降解，过量可能导致纤维化变化。
T0073	Octinoxate 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,甲氧基肉桂酸辛酯,Octyl methoxycinnamate,对甲氧基肉桂酸辛酯	Others	Others
	Octinoxate (Octyl 4-methoxycinnamate) 能够吸收来自太阳的 UV-B 射线，保护皮肤免受损伤，也可用于减少疤痕的外观，常用于是防晒霜和唇膏等化妆品中。
T3S0013	Ethyl trans-caffeate 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester	Others	Others
	Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) 具有抗炎作用。它是一种有前途的天然化合物，未来在慢性肝病中的应用。它是一种有效的化学预防化合物，可防止因太阳紫外线照射引起的皮肤癌变。它是与人胰腺α-淀粉酶复合的代表性抑制剂的高分辨率结构。它强烈抑制 JB6 Cl41细胞的肿瘤转化，无毒性。 PI3K、ERK1/2 和 p38 激酶活性在体外通过与 HOEC 直接结合而受到抑制。
TN2736	2',6'-Dihydroxy-4'-methoxyacetophenone	Antifection	Microbiology/Virology
	2',6'-Dihydroxy-4'-methoxyacetophenone is a phytoalexin after fungal inoculation with Botrytis cinerea or UV light irradiation, it has spore germination inhibition on Botrytis cinerea and Phomopsis perniciosa, with ED50 values of 45 and 410 uM, respective