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Cat. No. Product Name Target Signaling Pathways
T13954 UNC6852

Histone Methyltransferase; Ligands for Target Protein for PROTAC Chromatin/Epigenetic; PROTAC
UNC6852 包含一个 EED 配体 (IC50 = 247 nM) 和一个 von Hippel-Lindau 配体,是一种基于 PROTAC 的特异性多梳抑制复合物 2 (PRC2) 降解剂。
T17649 Boc-GABA-OH

Others; PROTAC Linker Others; PROTAC
Boc-GABA-OH 是一种 PROTAC linker,可用于 UNC6852 的合成。其中 UNC6852 是靶向 EED 的 PROTAC 降解剂。
T18664 (S,R,S)-AHPC-C3-NH2

VH032-C3-NH2

Others Others
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component in the synthesis of various PROTACs, including UNC6852. UNC6852 is a bivalent chemical degrader specifically targeting EED [1].
T18663 (S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)

(S,R,S)-AHPC-C3-NH2 TFA,VH032-C3-NH2 TFA

Others Others
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, suc
T17931 EED226-COOH

Others Others
EED226-COOH, derived from EED226, serves as a ligand targeting the EED protein for PROTAC applications. It attaches to a VHL ligand through a linker, culminating in the formation of UNC6852, which specifically degrades PRC2[1].

化合物

UNC6852
Cat.No: T13954
Synonym:
Target: Histone Methyltransferase, Ligands for Target Protein for PROTAC
Boc-GABA-OH
Cat.No: T17649
Synonym:
Target: Others, PROTAC Linker
(S,R,S)-AHPC-C3-NH2
Cat.No: T18664
Synonym: VH032-C3-NH2
Target: Others
(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)
Cat.No: T18663
Synonym: (S,R,S)-AHPC-C3-NH2 TFA,VH032-C3-NH2 TFA
Target: Others
EED226-COOH
Cat.No: T17931
Synonym:
Target: Others
TargetMol Loading
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